ReviewEuropean heart journal2023
Valvular heart disease: shifting the focus to the myocardium.
Review in European heart journal, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 40 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
40 citing papers in PubMed, 96 citations in OpenAlex.
- Exposure to TBBPA and polystyrene nanoplastics induces cardiac fibrosis via the activation of the ESR/H19/Wnt pathway.Redox biology · 2026Article
- Association Between the Degree of Extravalvular Cardiac Damage and the Severity of Aortic Stenosis.JACC. Advances · 2026Article
- SGLT-2 Inhibitors and Outcomes After Transcatheter Aortic Valve Implantation: A Systematic Review and Meta-Analysis.JACC. Advances · 2026Article
- End-stage valvular heart disease requiring heart transplantation: risk profile, surgical modifiers, and myocardial pathology.BMC cardiovascular disorders · 2026Article
- Relative aortic valve stiffness: a new parameter quantifying aortic stenosis.American journal of physiology. Heart and circulatory physiology · 2026Article
- Optimized Feature Selection and Deep Neural Networks to Improve Heart Disease Prediction.Journal of imaging informatics in medicine · 2026Article
- Accelerated Biological Aging, Genetic Predisposition, and Incident Valvular Heart Disease.JACC. Asia · 2026Article
- Association between pre-procedural computed tomography angiography-based global longitudinal strain and outcomes in patients undergoing transcatheter aortic valve implantation.Quantitative imaging in medicine and surgery · 2025Article
- The electrocardiogram reimagined: AI-ECG as a prognostic beacon for valvular heart disease.European heart journal · 2025Article
- Artificial intelligence-enhanced electrocardiography to predict regurgitant valvular heart diseases: an international study.European heart journal · 2025Article
- Understanding the Transvalvular Gradient in Aortic Stenosis: A Multifaceted Perspective.Journal of clinical medicine · 2025Review
- Predicting reverse remodeling following valve replacement in patients with valvular heart disease: a longitudinalEuropean journal of nuclear medicine and molecular imaging · 2025Article
- Development and validation of a novel score to predict adverse outcomes in paediatric congenital mitral regurgitation (PRIMARY): a multicentre cohort study.EClinicalMedicine · 2025Article
- Future of Valvular Heart Disease and Structural Heart Interventions: Why So Much Excitement?Journal of personalized medicine · 2025Article
- A new wearable e monitoring technology for evaluation of left ventricular remodeling after transcatheter aortic valve replacement.European heart journal. Digital health · 2025Article
- Sodium-Glucose Cotransporter 2 Inhibitors in Aortic Stenosis: Toward a Comprehensive Cardiometabolic Approach.International journal of molecular sciences · 2025Review
- Left-atrioventricular interaction and left-atrial deformation in patients with type 2 diabetes mellitus with or without chronic aortic regurgitation: a 3.0-T cardiac magnetic resonance feature-tracking study.Quantitative imaging in medicine and surgery · 2025Article
- Could SGLT2 inhibitors improve outcomes in patients with heart failure and significant valvular heart disease? Need for action.Heart failure reviews · 2025Review
- Factors influencing postoperative hyperbilirubinemia in valvular heart disease and establishment of a predictive model.Frontiers in cardiovascular medicine · 2025Article
- Contemporary diagnosis and treatment of valvular heart disease in Korea: a nationwide hospital-based registry study.Journal of cardiovascular imaging · 2024Article
Corrections and comments
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Authors and funding
7 authors at 5 institutions in 4 countries.
Funding
Abstract
Adverse cardiac remodelling is the main determinant of patient prognosis in degenerative valvular heart disease (VHD). However, to give an indication for valvular intervention, current guidelines include parameters of cardiac chamber dilatation or function which are subject to variability, do not directly reflect myocardial structural changes, and, more importantly, seem to be not sensitive enough in depicting early signs of myocardial dysfunction before irreversible myocardial damage has occurred. To avoid irreversible myocardial dysfunction, novel biomarkers are advocated to help refining indications for intervention and risk stratification. Advanced echocardiographic modalities, including strain analysis, and magnetic resonance imaging have shown to be promising in providing new tools to depict the important switch from adaptive to maladaptive myocardial changes in response to severe VHD. This review, therefore, summarizes the current available evidence on the role of these new imaging biomarkers in degenerative VHD, aiming at shifting the clinical perspective from a valve-centred to a myocardium-focused approach for patient management and therapeutic decision-making.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.