Evidence map›Paper›PMID 36167869›Full record

ArticleScientific reports2022

Detecting SARS-CoV-2 variants in wastewater and their correlation with circulating variants in the communities.

Lin Li, Timsy Uppal, Paul D Hartley, Andrew Gorzalski, Mark Pandori, Michael A Picker, Subhash C Verma, Krishna Pagilla

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 1 pooled it
2.9field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 1 synthesis or guideline pooled it, 31 citations in OpenAlex.

  1. Pooled it
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  10. Estimation of SARS-CoV-2 fitness gains from genomic surveillance data without prior lineage classification.Proceedings of the National Academy of Sciences of the United States of America · 2024
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Lin LiDepartment of Civil and Environmental Engineering, University of Nevada, MS258, Reno, NV, 89557, USA.
Timsy UppalDepartment of Microbiology and Immunology, University of Nevada, Reno School of Medicine, MS320, Reno, NV, 89557, USA.
Paul D HartleyNevada Genomics Center, University of Nevada, Reno, NV, 89557, USA.
Andrew GorzalskiNevada State Public Health Laboratory, Reno, NV, USA.
Mark PandoriNevada State Public Health Laboratory, Reno, NV, USA.
Michael A PickerSouthern Nevada Public Health Laboratory of the Southern Nevada Health District, Las Vegas, NV, USA.
Subhash C VermaDepartment of Microbiology and Immunology, University of Nevada, Reno School of Medicine, MS320, Reno, NV, 89557, USA. scverma@med.unr.edu.
Krishna PagillaDepartment of Civil and Environmental Engineering, University of Nevada, MS258, Reno, NV, 89557, USA. pagilla@unr.edu.
University of Nevada, Reno · USNevada Division of Public and Behavioral Health · USSouthern Nevada Health District · US

Funding

Outreach/Diversity/Pipeline ProjectP20GM103440 · NIGMS · UNIVERSITY OF NEVADA RENO · PI Eduardo A Robleto · 2012 to 2026
$58.0M
Tracking and EvaluationU54GM104944 · NIGMS · UNIVERSITY OF NEVADA LAS VEGAS · PI KUMAR, PARVESH · 2013 to 2023
$39.6M
NIGMS NIH HHS NOSI NOTGM-21-031NIGMS NIH HHS P20 GM103440NIGMS NIH HHS U54 GM104944
6 · The paper itself

Abstract

Detection of SARS-CoV-2 viral load in wastewater has been highly informative in estimating the approximate number of infected individuals in the surrounding communities. Recent developments in wastewater monitoring to determine community prevalence of COVID-19 further extends into identifying SARS-CoV-2 variants, including those being monitored for having enhanced transmissibility. We sequenced genomic RNA derived from wastewater to determine the variants of coronaviruses circulating in the communities. Wastewater samples were collected from Truckee Meadows Water Reclamation Facility (TMWRF) from November 2020 to June 2021. SARS-CoV-2 variants resulting from wastewater were compared with the variants detected in infected individuals' clinical specimens (nasal/nasopharyngeal swabs) during the same period and found conclusively in agreement. Therefore, wastewater monitoring for SARS-CoV-2 variants in the community is a feasible strategy as a complementary tool to clinical specimen testing in the latter's absence.

Indexed as

COVID-19SARS-CoV-2HumansRNARNA, ViralWastewaterRNARNA, ViralWastewater

Identifiers

PMID36167869
PMCPMC9514676
OpenAlexW4297327379

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.