Evidence map›Paper›PMID 36167853›Full record

ArticleEuropean journal of clinical pharmacology2022

Higher FORTA (Fit fOR The Aged) scores are associated with poor functional outcomes, dementia, and mortality in older people.

Farhad Pazan, Hanna Breunig, Christel Weiss, Susanne Röhr, Melanie Luppa, Michael Pentzek, Horst Bickel, Dagmar Weeg, Siegfried Weyerer, Birgitt Wiese and 8 more

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in European journal of clinical pharmacology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.9field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Article
  3. FORTA Score and Negative Outcomes in Older Adults: Insights from Italian Internal Medicine Wards.Medical principles and practice : international journal of the Kuwait University, Health Science Centre · 2025
    Article
  4. Article
  5. [The FORTA (Fit fOR The Aged) List].Innere Medizin (Heidelberg, Germany) · 2024
    Review
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors at 7 institutions in 1 country.

Farhad PazanClinical Pharmacology Mannheim, Medical Faculty Mannheim, Ruprecht-Karls-Heidelberg University, Theodor-Kutzer-Ufer 1-3, 68167, Mannheim, Germany.
Hanna BreunigClinical Pharmacology Mannheim, Medical Faculty Mannheim, Ruprecht-Karls-Heidelberg University, Theodor-Kutzer-Ufer 1-3, 68167, Mannheim, Germany.
Christel WeissDepartment of Medical Statistics, Biomathematics and Information Processing, Medical Faculty, University of Heidelberg, Mannheim, Germany.
Susanne RöhrInstitute of Social Medicine, Medical Faculty, Occupational Health and Public Health (ISAP), University of Leipzig, Leipzig, Germany.
Melanie LuppaInstitute of Social Medicine, Medical Faculty, Occupational Health and Public Health (ISAP), University of Leipzig, Leipzig, Germany.
Michael PentzekInstitute of General Practice, Medical Faculty, Heinrich-Heine-University Düsseldorf, Düsseldorf, Germany.
Horst BickelDepartment of Psychiatry, Technical University of Munich, Munich, Germany.
Dagmar WeegDepartment of Psychiatry, Technical University of Munich, Munich, Germany.
Siegfried WeyererMedical Faculty Mannheim, Central Institute of Mental Health, Heidelberg University, Mannheim, Germany.
Birgitt WieseInstitute for General Practice, Hannover Medical School, Hanover, Germany.
Hans-Helmut KönigDepartment of Health Economics and Health Services Research, University Medical Centre Hamburg-Eppendorf, Hamburg, Germany.
Christian BrettschneiderDepartment of Health Economics and Health Services Research, University Medical Centre Hamburg-Eppendorf, Hamburg, Germany.
Kathrin HeserDepartment of Neurodegenerative Diseases and Geriatric Psychiatry, University Hospital Bonn, Bonn, Germany.
Wolfgang MaierDepartment of Neurodegenerative Diseases and Geriatric Psychiatry, University Hospital Bonn, Bonn, Germany.
Martin SchererDepartment of Primary Medical Care, Center for Psychosocial Medicine, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
Steffi Riedel-HellerInstitute of Social Medicine, Medical Faculty, Occupational Health and Public Health (ISAP), University of Leipzig, Leipzig, Germany.
Michael Wagner *Department of Neurodegenerative Diseases and Geriatric Psychiatry, University Hospital Bonn, Bonn, Germany.
Martin Wehling *Clinical Pharmacology Mannheim, Medical Faculty Mannheim, Ruprecht-Karls-Heidelberg University, Theodor-Kutzer-Ufer 1-3, 68167, Mannheim, Germany. martin.wehling@medma.uni-heidelberg.de.ORCID http://orcid.org/0000-0003-1393-1691
Heidelberg University · DELeipzig University · DEUniversität Hamburg · DEUniversity Hospital Bonn · DETechnical University of Munich · DEHeinrich Heine University Düsseldorf · DEMedizinische Hochschule Hannover · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeHigher Fit fOR The Aged (FORTA) scores have been shown to be negatively associated with adverse clinical outcomes in older hospitalized patients. This has not been evaluated in other health care settings. The aim of this study was to examine the association of the FORTA score with relevant outcomes in the prospective AgeCoDe-AgeQualiDe cohort of community-dwelling older people. In particular, the longitudinal relation between the FORTA score and mortality and the incidence of dementia was evaluated.

methodsUnivariate and multivariate correlations between the FORTA score and activities of daily living (ADL) or instrumental activities of daily living (IADL) as well as comparisons between high vs. low FORTA scores were conducted.

resultsThe FORTA score was significantly correlated with ADL/IADL at baseline and at all follow-up visits (p < 0.0001). ADL/IADL results of participants with a low FORTA score were significantly better than in those with high FORTA scores (p < 0.0001). The FORTA score was also significantly (p < 0.0001) correlated with ADL/IADL in the multivariate analysis. Moreover, the mean FORTA scores of participants with dementia were significantly higher (p < 0.0001) than in those without dementia at follow-up visits 6 through 9. The mean FORTA scores of participants who died were significantly higher than those of survivors at follow-up visits 7 (p < 0.05), 8 (p < 0.001), and 9 (p < 0.001).

conclusionIn this study, an association between higher FORTA scores and ADL as well as IADL was demonstrated in community-dwelling older adults. Besides, higher FORTA scores appear to be linked to a higher incidence of dementia and even mortality.

Indexed as

Activities of Daily LivingDementiaAgedHumansIndependent LivingProspective StudiesDementiaInappropriate prescribingMultimorbidityOlder peoplePolypharmacy

Identifiers

PMID36167853
PMCPMC9546968
OpenAlexW4297324561

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.