ArticleTranslational psychiatry2022
Physical activity partly mediates the association between cognitive function and depressive symptoms.
Article in Translational psychiatry, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 2 of them syntheses that pooled it.
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Who cites it
12 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Effects of exercise on cognitive function in patients with depression: a three-level meta-analysis with dose-response and exploratory mediation analyses.The international journal of behavioral nutrition and physical activity · 2026Pooled it
- Physical Activity and Cognitive Decline Among Older Adults: A Systematic Review and Meta-Analysis.JAMA network open · 2024Pooled it
- How Life-Course Trajectories of Physical Activity Track With Cognitive Decline.Journal of physical activity & health · 2026Article
- Relationships of Cognitive Function With Subsequent Device-Measured Physical Activity and Sedentary Time in Healthy Individuals and Those With Bipolar Disorder: Findings From the UK Biobank.Acta psychiatrica Scandinavica · 2026Article
- Article
- Symptom Network Analysis Tools for Applied Researchers With Cross-Sectional and Panel Data - A Brief Overview and Multiverse Analysis.Psychological reports · 2025Review
- Bidirectional associations of physical activity and cognitive function in midlife adults: a longitudinal analysis across 26 years follow-up.American journal of epidemiology · 2025Article
- Interplay of Physical Activity, Muscle Strength, and Depression in Cognitive Impairment among Korean Older Adults: A Cross-sectional Study.Clinical psychopharmacology and neuroscience : the official scientific journal of the Korean College of Neuropsychopharmacology · 2025Article
- Mediating Role of Internet Use in Cognitive-Depressive Pathways: A Random Intercept Cross-Lagged Panel Modeling Approach.International journal of public health · 2025Article
- Neural correlates of approach-avoidance tendencies toward physical activity and sedentary stimuli: An MRI study.Imaging neuroscience (Cambridge, Mass.) · 2025Article
- Historic Cognitive Function Trajectories as Predictors of Sedentary Behavior and Physical Activity in Older Adults.The journals of gerontology. Series A, Biological sciences and medical sciences · 2024Article
- Directionality between cognitive function and daily physical activity patterns.Alzheimer's & dementia (New York, N. Y.)Article
Corrections and comments
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Authors and funding
5 authors.
Funding
Abstract
Cognitive function, physical activity, and depressive symptoms are intertwined in later life. Yet, the nature of the relationship between these three variables is unclear. Here, we aimed to determine which of physical activity or cognitive function mediated this relationship. We used large-scale longitudinal data from 51,191 adults 50 years of age or older (mean: 64.8 years, 54.7% women) from the Survey of Health, Ageing and Retirement in Europe (SHARE). Results of the longitudinal mediation analyses combined with autoregressive cross-lagged panel models showed that the model with physical activity as a mediator better fitted the data than the model with cognitive function as a mediator. Moreover, the mediating effect of physical activity was 8-9% of the total effect of cognitive function on depressive symptoms. Our findings suggest that higher cognitive resources favor the engagement in physical activity, which contributes to reduced depressive symptoms.
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