ArticleBMJ open2022
Impact of gestational hypertension and pre-eclampsia on preterm birth in China: a large prospective cohort study.
Article in BMJ open, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers, 2 of them syntheses that pooled it.
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Who cites it
37 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Hypertensive disorders of pregnancy may increase the risk of neurodevelopmental delay in the offspring: a systematic review with meta-analysis.Hypertension research : official journal of the Japanese Society of Hypertension · 2026Pooled it
- Global prevalence of preeclampsia, eclampsia, and HELLP syndrome: a systematic review and meta-analysis.Frontiers in reproductive health · 2025Pooled it
- Therapeutic Interventions for Preeclampsia: Integrating Placental and Maternal Perspectives.American journal of reproductive immunology (New York, N.Y. : 1989) · 2026Review
- Industrial emissions and risks of preterm and small-for-gestational-age birth: A population-based cohort study in Quebec, Canada.Environmental epidemiology (Philadelphia, Pa.) · 2026Article
- Sexually-dimorphic offspring outcomes following antenatal corticosteroids: a review of the evidence for congenital adrenal hyperplasia and preterm birth risk.Biology of sex differences · 2026Review
- Interaction between maternal CRP levels and diabetes on preterm delivery risk: a retrospective observation study.BMC pregnancy and childbirth · 2026Observational
- Risk factors for low birthweight among multinational mothers: results from the first population-based maternal and infant health monitoring system in the capital emirate of the United Arab Emirates.BMC pregnancy and childbirth · 2026Article
- Impact of early pregnancy body mass index and gestational weight gain on birth outcomes: Findings from a pregnancy cohort in South Delhi, India.PLOS global public health · 2026Article
- Maternal and foetal factors contributing to caesarean section rates at Chris Hani Baragwanath Academic Hospital, a tertiary care centre in South Africa.Journal of the colleges of medicine of South Africa · 2026Article
- The Protective Effect of Vitamin D Against Necroptosis in Preeclampsia.Journal of pregnancy · 2026Article
- Combined cord blood metabolomic and clinical signatures discriminate small for gestational age neonates in preeclampsia.Frontiers in endocrinology · 2026Article
- Adverse Materno-Foetal Outcomes of Pre-Eclampsia at a Rural Tertiary Hospital in the Eastern Cape Province of South Africa.International journal of environmental research and public health · 2025Article
- Unveiling the risks and outcomes of preeclampsia: a case-control study in the UAE.BMC pregnancy and childbirth · 2025Article
- Cardiovascular Disease in Pregnancy: When Two Hearts Beat as One.Diagnostics (Basel, Switzerland) · 2025Review
- Association between prenatal exposure to antihypertensive medication and neurodevelopmental and educational outcomes in children.Scientific reports · 2025Article
- Risk factors for severe maternal morbidity in patients with hypertensive disorder of pregnancy: A retrospective study.Pakistan journal of medical sciences · 2025Article
- Lipid metabolism dysregulation in umbilical cord plasma of newborns from mothers with preeclampsia is associated with neonatal physical parameters at birth.BMC pediatrics · 2025Article
- The Correlation Between Fetal Wellbeing and Umbilical Doppler Parameters in Pregnant Women with Gestational Hypertension.International journal of women's health · 2025Article
- Impact of Maternal Hyperglycemic and Hypertensive Disorders on Perinatal Outcomes Across the COVID-19 Pandemic.Women's health reports (New Rochelle, N.Y.) · 2025Article
- Early-onset preeclampsia/gestational hypertension may be associated with a low incidence of cerebral palsy at 3 years old in singleton very low-birth-weight infants born at 28-31 weeks of gestation (EOPE-DQ study): a multi-center retrospective cohort study in 2013-2016.Hypertension research : official journal of the Japanese Society of Hypertension · 2025Article
Corrections and comments
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Authors and funding
8 authors.
Funding
Abstract
objectiveTo investigate the impact of gestational hypertension and pre-eclampsia on preterm birth.
designThe data were collected from the China-US Collaborative Project for Neural Tube Defect Prevention; this was a large population-based cohort study. SETTING AND
participantsWe selected participants registered in two southern provinces, for whom we had exact information on gestational blood pressure and pregnancy outcomes, and who were not affected by chronic hypertension. In total, 200 103 participants were recruited from 1993 to 1995. OUTCOME MEASURES: Preterm birth was defined as a singleton pregnancy and birth before 37 gestational weeks.
resultsThe incidences of gestational hypertension and pre-eclampsia were 5.47% and 5.44%, respectively, for women who gave birth at full term, and 5.63% and 7.33%, respectively, for those who gave birth preterm. After adjusting for potential confounders, the risk ratios (RRs) of preterm birth in women with gestational hypertension and pre-eclampsia were 1.04 (95% CI 0.98 to 1.11) and 1.39 (95% CI 1.25 to 1.55), respectively. The associations were stronger for early-onset (<28 weeks of gestation) gestational hypertension (adjusted RR=2.13, 95% CI 1.71 to 2.65) and pre-eclampsia (adjusted RR=8.47, 95% CI 5.59 to 12.80).
conclusionsPre-eclampsia was associated with a higher risk of preterm birth. The early-onset gestational hypertension and pre-eclampsia were associated with more severe risks than late-onset conditions.
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