Evidence map›Paper›PMID 36167120›Full record

ArticleChest2023

Clinical Markers Associated With Risk of Suicide or Drug Overdose Among Individuals With Smoking Exposure: A Longitudinal Follow-up Study of the COPDGene Cohort.

Brigid A Adviento, Elizabeth A Regan, Barry J Make, MeiLan K Han, Marilyn G Foreman, Anand S Iyer, Surya P Bhatt, Victor Kim, Jessica Bon, Xavier Soler and 9 more

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Chest, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.0field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

19 authors at 14 institutions in 2 countries.

Brigid A AdvientoDepartment of Psychiatry, University of Iowa, Iowa City, IA; Department of Internal Medicine, University of Iowa, Iowa City, IA.
Elizabeth A ReganDivision of Rheumatology, Department of Medicine, National Jewish Health, Denver, CO.
Barry J MakeDivision of Pulmonary, Critical Care and Sleep Medicine, Department of Medicine, National Jewish Health, Denver, CO; Division of Pulmonary Sciences and Critical Care Medicine, Department of Medicine, University of Colorado School of Medicine, Aurora, CO.
MeiLan K HanDivision of Pulmonary and Critical Care Medicine, Department of Internal Medicine, University of Michigan, Ann Arbor, MI.
Marilyn G ForemanPulmonary and Critical Care Medicine Division, Morehouse School of Medicine, Atlanta, GA.
Anand S IyerDivision of Pulmonary, Allergy and Critical Care Medicine, Department of Medicine, The University of Alabama at Birmingham, Birmingham, AL.
Surya P BhattDivision of Pulmonary, Allergy and Critical Care Medicine, Department of Medicine, The University of Alabama at Birmingham, Birmingham, AL.
Victor KimDepartment of Thoracic Medicine and Surgery, Lewis Katz School of Medicine at Temple University, Philadelphia, PA.
Jessica BonDivision of Pulmonary, Allergy and Critical Care Medicine, Department of Medicine, University of Pittsburgh, Pittsburgh, PA; VA Pittsburgh Healthcare System, Pittsburgh, PA.
Xavier SolerDepartment of Pulmonary, Critical Care and Sleep Medicine, University of California San Diego, San Diego, CA.
Gregory L KinneyDepartment of Epidemiology, Colorado School of Public Health, University of Colorado, Aurora, CO.
Nicola A HananiaSection of Pulmonary and Critical Care Medicine, Baylor College of Medicine, Houston, TX.
Katherine E LoweCase Western Reserve University School of Medicine, Cleveland, OH.
Kristen E HolmDivision of Neurology and Behavioral Health, National Jewish Health, Denver, CO; Department of Community and Behavioral Health, Colorado School of Public Health, University of Colorado, Aurora, CO.
Abebaw M YohannesDepartment of Physical Therapy, Azusa Pacific University, Azusa, CA.
Gen ShinozakiDepartment of Psychiatry and Behavioral Sciences, Stanford University School of Medicine, Palo Alto, CA.
Karin F HothDepartment of Psychiatry, University of Iowa, Iowa City, IA; Iowa Neuroscience Institute, University of Iowa, Iowa City, IA. Electronic address: karin-hoth@uiowa.edu.
Jess G FiedorowiczOttawa Hospital, Ottawa Hospital Research Institute, and University of Ottawa, Ottawa, Ontario, Canada.
COPDGene Investigators
National Jewish Health · USUniversity of Alabama at Birmingham · USUniversity of Michigan · USUniversity of California System · USUniversity of Iowa · USVA Pittsburgh Healthcare System · USBaylor College of Medicine · USColorado School of Public Health · USMorehouse School of Medicine · USTemple University · USAzusa Pacific University · USStanford University · USUniversity of Ottawa · CAUniversity School · US

Funding

Genetic Epidemiology of COPDU01HL089897 · NHLBI · NATIONAL JEWISH HEALTH · PI CRAPO, JAMES D · 2007 to 2021
$56.9M
Genetic Epidemiology of COPDU01HL089856 · NHLBI · BRIGHAM AND WOMEN'S HOSPITAL · PI SILVERMAN, EDWIN K · 2007 to 2021
$20.7M
NHLBI NIH HHS U01 HL089856NHLBI NIH HHS U01 HL089897
6 · The paper itself

Abstract

backgroundStudies have shown that COPD and smoking are associated with increased suicide risk. To date, there are no prospective studies examining suicide risk among individuals with smoking exposure along a spectrum of pulmonary diseases ranging from normal spirometry to severe COPD. RESEARCH QUESTION: Which clinical variables predict death by suicide or overdose of indeterminate intent in a large cohort of individuals with smoking exposure within the Genetic Epidemiology of COPD (COPDGene) study? STUDY DESIGN AND

methodsWe studied data from 9,930 participants involved in COPDGene, a multisite, prospective cohort study of individuals with smoking exposure. Primary cause of adjudicated deaths was identified by using death certificates, family reports, and medical records. Time to death by suicide/overdose was examined as the primary outcome in Cox regression models including age, sex, race, BMI, pack-years, current smoking status, airflow limitation (FEV

resultsThe cohort was 47% female and 33% Black (67% White); they had a mean ± SD age of 59.6 ± 9.0 years and a mean FEV

interpretationIn this well-characterized cohort of individuals with smoking exposure with and without COPD, risk factors for suicide/overdose were identified that emphasize the subjective experience of illness over objective assessments of lung function.

Indexed as

Drug OverdosePulmonary Disease, Chronic ObstructiveAgedBiomarkersDyspneaFemaleFollow-Up StudiesForced Expiratory VolumeHumansMaleMiddle AgedProspective StudiesRisk FactorsSmokingBiomarkersCOPDoverdoseprospective cohort studysuicide deathstobacco smoking

Identifiers

PMID36167120
PMCPMC10083129
OpenAlexW4297178971

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.