Evidence map›Paper›PMID 36166837›Full record

ArticleACS sensors2022

Repeated and On-Demand Intracellular Recordings of Cardiomyocytes Derived from Human-Induced Pluripotent Stem Cells.

Jihyun Lee, Tobias Gänswein, Hasan Ulusan, Vishalini Emmenegger, Ardan M Saguner, Firat Duru, Andreas Hierlemann

Open access · greenAbstract read
In one paragraph

Article in ACS sensors, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
2.0field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 23 citations in OpenAlex.

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  8. Anthracycline Toxicity: Light at the End of the Tunnel?Annual review of pharmacology and toxicology · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Jihyun LeeBio Engineering Laboratory, ETH Zurich, 4058 Basel, Switzerland.ORCID 0000-0002-0135-0016
Tobias GänsweinBio Engineering Laboratory, ETH Zurich, 4058 Basel, Switzerland.ORCID 0000-0003-0323-6767
Hasan UlusanBio Engineering Laboratory, ETH Zurich, 4058 Basel, Switzerland.
Vishalini EmmeneggerBio Engineering Laboratory, ETH Zurich, 4058 Basel, Switzerland.
Ardan M SagunerCardiac Electrophysiology Division, University Heart Center Zurich, University Hospital Zurich, 8091 Zurich, Switzerland.
Firat DuruCardiac Electrophysiology Division, University Heart Center Zurich, University Hospital Zurich, 8091 Zurich, Switzerland.
Andreas HierlemannBio Engineering Laboratory, ETH Zurich, 4058 Basel, Switzerland.ORCID 0000-0002-3838-2468
ETH Zurich · CHUniversity Hospital of Zurich · CHUniversity of Zurich · CH

Funding

Swiss National Science Foundation 188910
6 · The paper itself

Abstract

Pharmaceutical compounds may have cardiotoxic properties, triggering potentially life-threatening arrhythmias. To investigate proarrhythmic effects of drugs, the patch clamp technique has been used as the gold standard for characterizing the electrophysiology of cardiomyocytes

Indexed as

Induced Pluripotent Stem CellsCardiotoxicityDrug Evaluation, PreclinicalHumansMicroelectrodesMyocytes, Cardiaccardiomyocyteselectroporationhigh-density microelectrode arraysinduced pluripotent stem cellsintracellular recordings

Identifiers

PMID36166837
PMCPMC7613763
OpenAlexW4297206743

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.