Evidence map›Paper›PMID 36166626›Full record

ArticleACS synthetic biology2022

Discovery and Heterologous Expression of Microginins from

Nádia Eusébio, Raquel Castelo-Branco, Diana Sousa, Marco Preto, Paul D'Agostino, Tobias A M Gulder, Pedro N Leão

Abstract read
In one paragraph

Article in ACS synthetic biology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed.

  1. Review
  2. Review
  3. Article
  4. Secondary metabolism ofApplied and environmental microbiology · 2026
    Review
  5. Article
  6. Review
  7. The Complete Genomes ofMicroorganisms · 2025
    Article
  8. Chemodiversity and Biotechnological Potential of Microginins.International journal of molecular sciences · 2025
    Review
  9. Review
  10. Article
  11. Review
  12. Article
  13. Genome Mining ofMicroorganisms · 2024
    Article
  14. Review
  15. Article
  16. Natural Products That Contain Higher Homologated Amino Acids.Chembiochem : a European journal of chemical biology · 2024
    Review
  17. More than just an eagle killer: The freshwater cyanobacteriumProceedings of the National Academy of Sciences of the United States of America · 2023
    Article
  18. Expression ofApplied and environmental microbiology · 2023
    Article
  19. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Nádia EusébioInterdisciplinary Centre of Marine and Environmental Research (CIIMAR/CIMAR), University of Porto, Avenida General Norton de Matos, s/n, 4450-208 Matosinhos, Portugal.
Raquel Castelo-BrancoInterdisciplinary Centre of Marine and Environmental Research (CIIMAR/CIMAR), University of Porto, Avenida General Norton de Matos, s/n, 4450-208 Matosinhos, Portugal.
Diana SousaInterdisciplinary Centre of Marine and Environmental Research (CIIMAR/CIMAR), University of Porto, Avenida General Norton de Matos, s/n, 4450-208 Matosinhos, Portugal.
Marco PretoInterdisciplinary Centre of Marine and Environmental Research (CIIMAR/CIMAR), University of Porto, Avenida General Norton de Matos, s/n, 4450-208 Matosinhos, Portugal.
Paul D'AgostinoChair of Technical Biochemistry, Technical University of Dresden, Bergstraße 66, 01069 Dresden, Germany.ORCID 0000-0002-8323-5416
Tobias A M GulderChair of Technical Biochemistry, Technical University of Dresden, Bergstraße 66, 01069 Dresden, Germany.ORCID 0000-0001-6013-3161
Pedro N LeãoInterdisciplinary Centre of Marine and Environmental Research (CIIMAR/CIMAR), University of Porto, Avenida General Norton de Matos, s/n, 4450-208 Matosinhos, Portugal.ORCID 0000-0001-5064-9164

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Microginins are a large family of cyanobacterial lipopeptide protease inhibitors. A hybrid polyketide synthase/non-ribosomal peptide synthetase biosynthetic gene cluster (BGC) found in several microginin-producing strains─

Indexed as

CyanobacteriaMicrocystisAmino AcidsLipopeptidesPolyketide SynthasesProtease InhibitorsTyrosineAmino AcidshomotyrosineLipopeptidesPolyketide SynthasesProtease InhibitorsTyrosinebiosynthesiscyanobacteriadirect pathway cloning (DiPaC)heterologous expressionmicrogininsnatural products

Identifiers

PMID36166626
PMCPMC9594780

What OpenQuestion holds

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LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.