ArticleInflammatory bowel diseases2023
The Impact of Disease Activity on Sexual and Erectile Dysfunction in Patients With Inflammatory Bowel Disease.
Article in Inflammatory bowel diseases, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 13 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
13 citing papers in PubMed, 28 citations in OpenAlex.
- Sexual dysfunction is highly prevalent in patients with active perianal fistulizing Crohn's disease: Outcomes from a large national prospective cohort study.Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland · 2026Article
- Sexual Functioning of Patients with Inflammatory Bowel Disease.Journal of clinical medicine · 2026Article
- Sexuality and Intimacy in Inflammatory Bowel Disease: A Phenomenological Study.Healthcare (Basel, Switzerland) · 2026Article
- Health Maintenance and Unique Health Needs of the Perimenopausal and Postmenopausal Woman with Inflammatory Bowel Disease.Digestive diseases and sciences · 2025Review
- Sexual dysfunctions in inflammatory bowel disease: role of Mediterranean diet and quality of life.Andrology · 2025Observational
- Discovering a new paradigm: Gut microbiota as a central modulator of sexual health.World journal of gastrointestinal pathophysiology · 2025Review
- Effects of inflammatory bowel diseases on sexual function in women.Irish journal of medical science · 2025Article
- Sexual Health in Women with Inflammatory Bowel Diseases: A Narrative Review.Healthcare (Basel, Switzerland) · 2025Review
- Associations with sexual dysfunction among a Canadian cohort with inflammatory bowel disease.Journal of the Canadian Association of Gastroenterology · 2025Article
- Exploring intimacy and family planning in Inflammatory Bowel Diseases: a qualitative study.Annals of medicine · 2024Article
- Sexual and reproductive health considerations in the care of young adults with inflammatory bowel disease: A multidisciplinary conversation.Health care transitions · 2024Article
- Insights into disability and psycho-social care of patients with inflammatory bowel disease.Frontiers in medicine · 2024Review
- Relationship between inflammatory bowel disease and erectile dysfunction: a 2-sample Mendelian randomization study.Sexual medicine · 2023Article
Corrections and comments
- Erratum issued
Authors and funding
7 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundIncreased disease activity may be a risk factor for sexual dysfunction (SD) in patients with inflammatory bowel disease (IBD). This study investigated associations between objective measures of disease activity and sexual function.
methodsAdults with IBD undergoing ileocolonoscopy were prospectively recruited. Demographic, sexual function (Female Sexual Function Index and International Index of Erectile Function), disease activity (endoscopic, biomarker, and symptoms), psychological symptoms, and quality-of-life data were collected. Rates of SD and erectile dysfunction (ED) were compared between patients with active and inactive inflammation and symptoms using the Fisher's exact test. Logistic regression examined associations between SD and ED, and disease characteristics and psychological symptoms.
resultsA total of 159 participants were included, 97 had Crohn's disease and 85 were women. SD was reported in 36 of 59 and 13 of 59 sexually active women and men, respectively and ED in 22 of 59 sexually active men. Rates of SD and ED were similar between individuals with active and inactive IBD based on endoscopic indices (P > .05) and biomarkers (P > .05). Women with active IBD symptoms experienced significantly higher rates of SD (P < .05), but men did not (P > .05). Multivariable logistic regression identified that symptoms of severe depression (odds ratio, 5.77; 95% confidence interval, 1.59-20.94) were associated with SD in women, and severe anxiety (odds ratio, 15.62; 95% confidence interval, 1.74-140.23) was associated with ED in men.
conclusionsObjective measures of disease activity are not associated with SD or ED in patients with IBD. Clinicians should consider concomitant psychological symptoms contributing to the sexual health of patients with IBD.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.