Evidence map›Paper›PMID 36166445›Full record

ArticlePloS one2022

Risk factors of early mortality among COVID-19 deceased patients in Addis Ababa COVID-19 care centers, Ethiopia.

Taye Ashine Mezgebu, Migbar Mekonnen Sibhat, Melsew Tsegaw Getnet, Kassie Tiruneh Gebeyehu, Wuletaw Zewde Chane, Edmialem Mesfin Getahun, Asaminew Sane Habtamu, Hailu Beyene Asmare, Melke Mengistie Ambaw

Abstract read
In one paragraph

Article in PloS one, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Taye Ashine MezgebuSchools of Nursing, College of Health Science and Medicine, Wachemo University, Hosanna, Ethiopia.ORCID 0000-0002-9656-9327
Migbar Mekonnen SibhatCollege of Health Science and Medicine, Dilla University, Dilla, Ethiopia.
Melsew Tsegaw GetnetSaint Paul's Hospital Millennium Medical College, Millennium COVID-19 Care Center, Addis Ababa, Ethiopia.
Kassie Tiruneh GebeyehuCollege of Health Science and Medicine, Dilla University, Dilla, Ethiopia.
Wuletaw Zewde ChaneSaint Paul's Hospital Millennium Medical College, Millennium COVID-19 Care Center, Addis Ababa, Ethiopia.ORCID 0000-0003-4241-6437
Edmialem Mesfin GetahunSaint Paul's Hospital Millennium Medical College, Millennium COVID-19 Care Center, Addis Ababa, Ethiopia.
Asaminew Sane HabtamuSchool of Nursing, College of Health Science and Medicine, Jimma University, Jimma, Ethiopia.
Hailu Beyene AsmareSchool of Nursing, College of Health Science and Medicine, Wolaita Sodo University, Sodo, Ethiopia.
Melke Mengistie AmbawDepartment of Nursing, Arba Minch College of Sciences, Arba Minch, Ethiopia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundSevere acute respiratory syndrome coronavirus-2 is a global health care problem with high mortality. Despite early mortality seeming alarming, data regarding factors that lead to increased early mortality of COVID 19 patients is not well-documented yet. The objective of this study was to identify the risk factors of early mortality in patients with confirmed COVID-19 infections. METHODOLOGY: A case-control study design was employed. With this, a total of 261 COVID-19 deceased recordings were reviewed. The cases of the study were recordings of patients deceased within three days of intensive care unit admission whereas, the rest 187 were recordings of patients who died after three days of admission. Data were collected using an extraction checklist, entered into Epi data version 4.4.2.2, and analyzed by SPSS version 25. After the description, binary logistic regression was run to conduct bivariate and multivariable analyses. Finally, statistical significance was declared at p-value <0.05, and an adjusted odds ratio with a 95% confidence interval was used to report the strength of association.

resultThe analysis was performed on 261 (87 cases and 174 controls) recordings. About 62.5% of the participants were aged above 65 years and two-thirds were males. The presence of cardiovascular disease (AOR = 4.79, with 95%CI: 1.73, 13.27) and bronchial-asthma (AOR = 6.57; 95% CI: 1.39, 31.13) were found to have a statistically significant association with early mortality. The existence of complications from COVID-19 (AOR = 0.22; 95% CI: 0.07, 0.74) and previous history of COVID-19 infection (AOR = 0.17, 95% CI: 0.04, 0.69) were associated with decreased risk of early mortality.

conclusionsHaving cardiovascular diseases and bronchial asthma was associated with an increased risk of early mortality. Conversely, the presence of intensive care unit complications and previous history of COVID-19 infection were associated with decreased risk of early mortality.

Indexed as

COVID-19AgedCase-Control StudiesCross-Sectional StudiesEthiopiaFemaleHumansMaleRisk Factors

Identifiers

PMID36166445
PMCPMC9514640

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.