Evidence map›Paper›PMID 36166080›Full record

ArticleEuropean journal of nuclear medicine and molecular imaging2023

Reproducibility of [18F]FDG PET/CT liver SUV as reference or normalisation factor.

Gerben J C Zwezerijnen, Jakoba J Eertink, Maria C Ferrández, Sanne E Wiegers, Coreline N Burggraaff, Pieternella J Lugtenburg, Martijn W Heymans, Henrica C W de Vet, Josée M Zijlstra, Ronald Boellaard

Abstract readComment
In one paragraph

Article in European journal of nuclear medicine and molecular imaging, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed.

  1. Trial
  2. Article
  3. An integrated PET/CT simulation framework for virtual imaging trials and quantitative performance evaluation.Physica medica : PM : an international journal devoted to the applications of physics to medicine and biology : official journal of the Italian Association of Biomedical Physics (AIFB) · 2026
    Article
  4. Article
  5. Article
  6. IntegratedEJNMMI research · 2026
    Article
  7. Article
  8. Article
  9. Development and validation of anAnnals of nuclear medicine · 2025
    Article
  10. Article
  11. Article
  12. Pediatric radiology · 2025
    Article
  13. Article
  14. Diagnostic and prognostic role ofEJNMMI research · 2025
    Article
  15. In-ovo imaging using ostrich eggs: biodistribution of F-18-FDG in ostrich embryos.Experimental biology and medicine (Maywood, N.J.) · 2025
    Article
  16. Review
  17. Challenging the significance of SUV-based parameters in a large-scale retrospective study on lung lesions.Cancer imaging : the official publication of the International Cancer Imaging Society · 2024
    Article
  18. Healthy tissue metabolism assessed by [Scientific reports · 2024
    Article
  19. Letter to the Editor: FDG Liver Biodistribution.European journal of nuclear medicine and molecular imaging · 2024
    Article
  20. Mitigating SUV uncertainties using total body PET imaging.European journal of nuclear medicine and molecular imaging · 2024
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

10 authors.

Gerben J C ZwezerijnenRadiology and Nuclear Medicine, Amsterdam UMC Location Vrije Universiteit Amsterdam, Amsterdam, The Netherlands.ORCID http://orcid.org/0000-0002-9571-9362
Jakoba J EertinkCancer Center Amsterdam, Imaging and Biomarkers, Amsterdam, The Netherlands.ORCID http://orcid.org/0000-0002-6094-0016
Maria C FerrándezRadiology and Nuclear Medicine, Amsterdam UMC Location Vrije Universiteit Amsterdam, Amsterdam, The Netherlands.
Sanne E WiegersRadiology and Nuclear Medicine, Amsterdam UMC Location Vrije Universiteit Amsterdam, Amsterdam, The Netherlands.ORCID http://orcid.org/0000-0003-3698-8121
Coreline N BurggraaffAmsterdam UMC Location Vrije Universiteit Amsterdam, Hematology, Amsterdam, The Netherlands.ORCID http://orcid.org/0000-0001-5863-6528
Pieternella J LugtenburgErasmus MC Cancer Institute, University Medical Center, Hematology, Rotterdam, The Netherlands.ORCID http://orcid.org/0000-0002-6735-8651
Martijn W HeymansEpidemiology and Data Science, Amsterdam UMC Location Vrije Universiteit Amsterdam, De Boelelaan 1117, Amsterdam, The Netherlands.ORCID http://orcid.org/0000-0002-3889-0921
Henrica C W de VetEpidemiology and Data Science, Amsterdam UMC Location Vrije Universiteit Amsterdam, De Boelelaan 1117, Amsterdam, The Netherlands.ORCID http://orcid.org/0000-0002-5454-2804
Josée M ZijlstraCancer Center Amsterdam, Imaging and Biomarkers, Amsterdam, The Netherlands.ORCID http://orcid.org/0000-0003-1074-5922
Ronald BoellaardRadiology and Nuclear Medicine, Amsterdam UMC Location Vrije Universiteit Amsterdam, Amsterdam, The Netherlands. r.boellaard@amsterdamumc.nl.ORCID http://orcid.org/0000-0002-0313-5686

Funding

KWF Kankerbestrijding VU 2018-11648
6 · The paper itself

Abstract

introductionAlthough visual and quantitative assessments of [18F]FDG PET/CT studies typically rely on liver uptake value as a reference or normalisation factor, consensus or consistency in measuring [18F]FDG uptake is lacking. Therefore, we evaluate the variation of several liver standardised uptake value (SUV) measurements in lymphoma [18F]FDG PET/CT studies using different uptake metrics.

methodsPET/CT scans from 34 lymphoma patients were used to calculate SUVmax

resultsGenerally, SUVmax

conclusionSUVmean

trial registrationEudraCT: 2006-005,174-42, 01-08-2008.

Indexed as

Fluorodeoxyglucose F18Positron Emission Tomography Computed TomographyHumansLiverRadiopharmaceuticalsReproducibility of ResultsFluorodeoxyglucose F18Radiopharmaceuticals[18F]FDG PET/CTLiver uptakeReferenceVOI

Identifiers

PMID36166080
PMCPMC9816285

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.