ArticleEuropean journal of nuclear medicine and molecular imaging2023
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Article in European journal of nuclear medicine and molecular imaging, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
6 citing papers in PubMed, 13 citations in OpenAlex.
- Dark seasons enhance brain and brown adipose tissue interactions related to mu-opioid receptor signaling.European journal of nuclear medicine and molecular imaging · 2025Article
- Pre-fertilization-origin preservation of brown fat-mediated energy expenditure in humans.Nature metabolism · 2025Article
- Seasonal variation in D2/3 dopamine receptor availability in the human brain.European journal of nuclear medicine and molecular imaging · 2024Article
- Investigation of [Scientific reports · 2024Article
- Does seasonal variation affect the neuroimmune system? A retrospective [Neuroscience letters · 2024Article
- Secretin modulates appetite via brown adipose tissue-brain axis.European journal of nuclear medicine and molecular imaging · 2023Article
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Authors and funding
19 authors at 4 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposePhotoperiod determines the metabolic activity of brown adipose tissue (BAT) and affects the food intake and body mass of mammals. Sympathetic innervation of the BAT controls thermogenesis and facilitates physiological adaption to seasonal changes, but the exact mechanism remains elusive. Previous studies have shown that central opioid signaling regulates BAT thermogenesis, and that the expression of the brain mu-opioid receptor (MOR) varies seasonally. Therefore, it is important to know whether MOR expression in BAT shows seasonal variation.
methodsWe determined the effect of photoperiod on BAT MOR availability using [
resultsLong photoperiod was associated with low MOR expression in BAT (β = - 0.04, 95% confidence interval: - 0.07, - 0.01), but not in muscles. We confirmed the expression of MOR in BAT and muscle using immunofluorescence staining.
conclusionPhotoperiod affects MOR availability in BAT. Sympathetic innervation of BAT may influence thermogenesis via the peripheral MOR system. The present study supports the utility of [
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.