GuidelineJAMA2022
Screening for Syphilis Infection in Nonpregnant Adolescents and Adults: US Preventive Services Task Force Reaffirmation Recommendation Statement.
Guideline in JAMA, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
32 citing papers in PubMed, 1 synthesis or guideline pooled it, 56 citations in OpenAlex.
- [Preventive activities in women: PAPPS 2024 update].Atencion primaria · 2024Guideline
- A Statewide Recommendation for Opt-Out Syphilis Screening in Nonpregnant Adults: Rationale and Evidence-to-Decision Framework.AJPM focus · 2026Article
- Evaluation of a Real-Time Knowledge Exchange Network Supporting Syphilis Rapid Testing and Immediate Treatment in Seven Public Health Units in Ontario, Canada.Learning health systems · 2026Article
- Clearance ofEClinicalMedicine · 2026Article
- Innovations and Challenges in Syphilis Screening and Prevention Among Men Who Have Sex With Men: A Scoping Review.Sexually transmitted diseases · 2026Article
- Syphilis-related mortality in the United States, 2021-2025: trends, demographic disparities, and clinical implications.BMC infectious diseases · 2026Article
- Frequent emergency department utilization and syphilis case profiles in the Sentara healthcare system: a retrospective cross-sectional analysis in Hampton Roads.BMC public health · 2026Article
- Characterising the rate of syphilis diagnosis among people incarcerated in state-level prisons: a cohort study in Washington state 2013-2023.Sexually transmitted infections · 2026Article
- A Diagnostic Pitfall: Secondary Syphilis Mimicking Psoriasis in a Patient With Alcoholic Liver Disease.Cureus · 2026Article
- Blood Culture-Negative Cardiovascular Syphilis in an Untreated HIV-Positive Man.The American journal of case reports · 2026Article
- Epidemiological trends and spatiotemporal distribution of syphilis in Nagasaki Prefecture, Japan, 2014-2023.Frontiers in public health · 2026Article
- Article
- Comparative performance of the traditional and reverse diagnostic algorithms for syphilis in pregnancy.Pregnancy (Hoboken, N.J.) · 2026Article
- Co-infection of Oncogenic Human Papillomavirus 16 Genotype in Genital Warts: A Case Report.Cureus · 2026Article
- Syphilis Screening and Treatment at a Large Urban Jail.Sexually transmitted diseases · 2025Article
- The perspective of socially vulnerable youth on healthcare services: a Portuguese cross-sectional study.Archives of public health = Archives belges de sante publique · 2025Article
- Diagnostic Properties of Different Serological Methods for Syphilis Testing in Brazil.Diagnostics (Basel, Switzerland) · 2025Article
- Assessing the impact of HIV self-testing on diagnosis rates in vulnerable groups in belo horizonte, Brazil: A cross-sectional analysis.Public health in practice (Oxford, England) · 2025Article
- Malignant Syphilis Mimicking Lymphoma in HIV: A Challenging Case and a Review of Literature Focusing on the Role of HIV and Syphilis Coinfection.Microorganisms · 2025Review
- HIV Incidence and Associated Risk Factors Among Young Men Who Have Sex With Men in Tianjin, China: Retrospective Cohort Study.JMIR public health and surveillance · 2025Article
Corrections and comments
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Authors and funding
17 authors at 11 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Importance: Syphilis is a sexually transmitted infection that can progress through different stages (primary, secondary, latent, and tertiary) and cause serious health problems if left untreated. Reported cases of primary and secondary syphilis in the US increased from a record low of 2.1 cases per 100 000 population in 2000 and 2001 to 11.9 cases per 100 000 population in 2019. Men account for the majority of cases (83% of primary and secondary syphilis cases in 2019), and rates among women nearly tripled from 2015 to 2019. Objective: To reaffirm its 2016 recommendation, the US Preventive Services Task Force (USPSTF) commissioned a reaffirmation evidence update focusing on targeted key questions evaluating the performance of risk assessment tools and the benefits and harms of screening for syphilis in nonpregnant adolescents and adults. Population: Asymptomatic, nonpregnant adolescents and adults who have ever been sexually active and are at increased risk for syphilis infection. Evidence Assessment: Using a reaffirmation process, the USPSTF concludes with high certainty that there is a substantial net benefit of screening for syphilis infection in nonpregnant persons who are at increased risk for infection. Recommendation: The USPSTF recommends screening for syphilis infection in persons who are at increased risk for infection. (A recommendation).
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.