ReviewRadiology2022
Microvascular Flow Imaging: A State-of-the-Art Review of Clinical Use and Promise.
Review in Radiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 102 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
102 citing papers in PubMed, 1 synthesis or guideline pooled it, 136 citations in OpenAlex.
- Radiofrequency Ablation for Recurrent Thyroid Cancers: 2025 Korean Society of Thyroid Radiology Guideline.Korean journal of radiology · 2025Guideline
- Evaluation of the pharmacokinetics, pharmacodynamics, and liver ultrasound imaging characteristics of a novel perfluoropropane microbubble in Chinese volunteers.Frontiers in pharmacology · 2025Trial
- A Data-Efficient Computational Framework for Reconstruction and Simulation of Microcirculatory Perfusion.Microcirculation (New York, N.Y. : 1994) · 2026Article
- Evaluation of Microvascular Flow Imaging and Power Doppler Ultrasonography in an Equine Model of Induced Superficial Digital Flexor Tendonitis.Veterinary radiology & ultrasound : the official journal of the American College of Veterinary Radiology and the International Veterinary Radiology Association · 2026Article
- Superresolution US Imaging of Rabbit Lymph Node Microvasculature for Metastasis Diagnosis.Radiology. Imaging cancer · 2026Article
- Multimodal Ultrasound Characterization of a Testicular Leydig Cell Tumor With Emphasis on Microvascular Flow Imaging Findings: A Case Report and Literature Review.Journal of clinical ultrasound : JCU · 2026Review
- Multiparametric Ultrasound for Characterisation of Testicular Lesions: Beyond Orchiectomy.Diagnostics (Basel, Switzerland) · 2026Review
- In Vivo Visualization and Quantification of Dermal Nevus Microvasculature Using Super-Resolution Ultrasound of Erythrocytes.Diagnostics (Basel, Switzerland) · 2026Article
- Ultrasound microflow imaging for the evaluation of inflammation associated with superficial vein thrombosis: a proof-of-concept case report.Quantitative imaging in medicine and surgery · 2026Article
- The "snow globe" sign: a microvascular flow imaging artifact in cystic lesions, and the role of dispersed internal debris.Abdominal radiology (New York) · 2026Article
- Review
- Article
- [Ultrasound technology's new application in the diagnosis and treatment of liver cancer].Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology · 2026Review
- Novel markers on microvascular flow imaging for identifying holoprosencephaly.BMC medical imaging · 2026Article
- Article
- Increased parotid microvascularity without stiffness differences in children with celiac disease.Pediatric radiology · 2026Article
- Non-contrast microvascular flow imaging in abdominal ultrasound: a pictorial essay.Journal of ultrasound · 2026Review
- Non-invasive ultrasound assessment of chronic liver disease: current position and future directions for a "one-stop" liver ultrasound approach.Insights into imaging · 2026Article
- CEUS in Atypical Renal Cystic Masses: How, When and Why.Medicina (Kaunas, Lithuania) · 2026Review
- Microvascular flow imaging in musculoskeletal ultrasound: from technical innovation to clinical integration.Journal of ultrasonography · 2026Review
42 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Vascular imaging with color and power Doppler is a useful tool in the assessment of various disease processes. Assessment of blood flow, from infarction and ischemia to hyperemia, in organs, neoplasms, and vessels, is used in nearly every US investigation. Recent developments in this area are sensitive to small-vessel low velocity flow without use of intravenous contrast agents, known as microvascular flow imaging (MVFI). MVFI is more sensitive in detection of small vessels than color, power, and spectral Doppler, reducing the need for follow-up contrast-enhanced US (CEUS), CT, and MRI, except when arterial and venous wash-in and washout characteristics would be helpful in diagnosis. Varying clinical applications of MVFI are reviewed in adult and pediatric populations, including its technical underpinnings. MVFI shows promise in assessment of several conditions including benign and malignant lesions in the liver and kidney, acute pathologic abnormalities in the gallbladder and testes, and superficial lymph nodes. Future potential of MVFI in different conditions (eg, endovascular repair) is discussed. Finally, clinical cases in which MVFI correlated and potentially obviated additional CEUS, CT, or MRI are shown.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.