Evidence map›Paper›PMID 36165644›Full record

ArticleApplied and environmental microbiology2022

Synbiotic Intervention with Lactobacilli, Bifidobacteria, and Inulin in Healthy Volunteers Increases the Abundance of Bifidobacteria but Does Not Alter Microbial Diversity.

Ingrid Maria Cecilia Rubin, Sarah Mollerup, Christa Broholm, Adam Baker, Mona Katrine Alberthe Holm, Martin Schou Pedersen, Mette Pinholt, Henrik Westh, Andreas Munk Petersen

Open access · greenAbstract read
In one paragraph

Article in Applied and environmental microbiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
1.6field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 19 citations in OpenAlex.

  1. Eight weeks of treatment with probioticFrontiers in nutrition · 2025
    Trial
  2. Review
  3. Article
  4. Article
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  7. Survival and safety evaluation ofMicrobiology spectrum · 2025
    Article
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  10. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Ingrid Maria Cecilia Rubin *Department of Clinical Microbiology, Copenhagen University Hospital-Amager and Hvidovre, Copenhagen, Denmark.ORCID 0000-0002-6158-2927
Sarah Mollerup *Department of Clinical Microbiology, Copenhagen University Hospital-Amager and Hvidovre, Copenhagen, Denmark.ORCID 0000-0003-2429-4018
Christa BroholmChr. Hansen A/S, Human Health, Hoersholm, Denmark.
Adam BakerChr. Hansen A/S, Human Health, Hoersholm, Denmark.
Mona Katrine Alberthe HolmDepartment of Clinical Microbiology, Copenhagen University Hospital-Amager and Hvidovre, Copenhagen, Denmark.
Martin Schou PedersenDepartment of Clinical Microbiology, Copenhagen University Hospital-Amager and Hvidovre, Copenhagen, Denmark.
Mette PinholtDepartment of Clinical Microbiology, Copenhagen University Hospital-Amager and Hvidovre, Copenhagen, Denmark.
Henrik WesthDepartment of Clinical Microbiology, Copenhagen University Hospital-Amager and Hvidovre, Copenhagen, Denmark.
Andreas Munk PetersenDepartment of Clinical Microbiology, Copenhagen University Hospital-Amager and Hvidovre, Copenhagen, Denmark.
Amager Hospital · DKChr. Hansen (Denmark) · DKUniversity of Copenhagen · DK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Synbiotics combine probiotics and prebiotics and are being investigated for potential health benefits. In this single-group-design trial, we analyzed changes in the gut microbiome, stool quality, and gastrointestinal well-being in 15 healthy volunteers after a synbiotic intervention comprising Lacticaseibacillus rhamnosus (LGG), Lactobacillus acidophilus (LA-5), Lacticaseibacillus paracasei subsp.

Indexed as

Bifidobacterium animalisProbioticsSynbioticsBifidobacteriumFecesHealthy VolunteersHumansInulinLactobacillusLactobacillus acidophilusPrebioticsInulinPrebioticsbifidobacteriafecalinulinlactobacillimetagenomicsmicrobiomeprebioticsprobioticsshotgunsynbiotics

Identifiers

PMID36165644
PMCPMC9552601
OpenAlexW4297251291

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.