ArticleVeterinary surgery : VS2022
Outcome of cranial cruciate ligament replacement with an enhanced polyethylene terephthalate implant in the dog: A pilot clinical trial.
Article in Veterinary surgery : VS, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Who cites it
6 citing papers in PubMed, 6 citations in OpenAlex.
- Zlig ligament reconstruction versus tibial plateau leveling osteotomy for cranial cruciate ligament rupture in dogs: a prospective controlled study.Frontiers in veterinary science · 2026Article
- Image based three-dimensional kinematic mapping to optimize femoral tunnel placement for intra-articular cranial cruciate ligament reconstruction in dogs.Frontiers in veterinary science · 2026Article
- Intra-Articular Surgical Reconstruction of a Canine Cranial Cruciate Ligament Using an Ultra-High-Molecular-Weight Polyethylene Ligament: Case Report with Six-Month Clinical Outcome.Veterinary sciences · 2024Article
- Osteoarthritis, adipokines and the translational research potential in small animal patients.Frontiers in veterinary science · 2024Review
- The effect of joint orientation on passive movement of the dog's stifle.Frontiers in veterinary science · 2023Article
- Outcome of cranial cruciate ligament replacement with an enhanced polyethylene terephthalate implant in the dog: A pilot clinical trial.Veterinary surgery : VS · 2022Article
Corrections and comments
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveTo assess the 6-month outcome and survival of enhanced polyethylene terephthalate (PET) implants as a replacement for the cranial cruciate ligament (CCL) in dogs with spontaneous CCL disease (CCLD). STUDY
designPilot, prospective case series. ANIMALS: Ten client-owned large breed dogs with unilateral spontaneous CCLD.
methodsDogs were evaluated before and 6 months after intra-articular placement of a PET implant with the Liverpool Osteoarthritis in Dogs questionnaire and force platform gait analysis. Arthroscopy was performed 6 months after surgery to visually assess implant integrity.
resultsScores on owner questionnaires and limb asymmetry improved in all dogs that reached the 6-month time point, by 51.7% (p = .008) and 86% (p = .002), respectively. The PET implant appeared intact and functioning in two stifles, partially intact and functioning in four stifles and completely torn in three stifles. One dog had an implant infection and was removed from the study. Evidence of deterioration and tearing occurred in the midbody of the implant.
conclusionAlthough function improved over the course of this study, only 2/10 implants appeared intact 6 months after placement. CLINICAL SIGNIFICANCE: Implant survivability prohibits further clinical investigation using this implant.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.