Evidence map›Paper›PMID 36165202›Full record

ArticleJournal of immunology (Baltimore, Md. : 1950)2022

Transcriptomic Profiling Identifies CD8

Barbara Altendorfer, Michael Stefan Unger, Rodolphe Poupardin, Anna Hoog, Daniela Asslaber, Iris Karina Gratz, Heike Mrowetz, Ariane Benedetti, Diana Marisa Bessa de Sousa, Richard Greil and 4 more

Open access · bronzeAbstract read
In one paragraph

Article in Journal of immunology (Baltimore, Md. : 1950), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 50 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
50citing papers in PubMed, 1 pooled it
5.7field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

50 citing papers in PubMed, 1 synthesis or guideline pooled it, 73 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Review
  4. Aged circulating CD8Immunity · 2026
    Article
  5. Review
  6. Article
  7. Immune signaling and function in neurodegeneration.The Journal of clinical investigation · 2026
    Review
  8. Article
  9. Article
  10. Review
  11. Review
  12. Article
  13. Article
  14. Article
  15. CD103Nature communications · 2025
    Article
  16. Article
  17. Granzyme KNature immunology · 2025
    Article
  18. Article
  19. Review
  20. CD28BMC neurology · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 3 institutions in 3 countries.

Barbara AltendorferInstitute of Molecular Regenerative Medicine, Paracelsus Medical University, Salzburg, Austria.ORCID 0000-0003-3669-5206
Michael Stefan UngerInstitute of Molecular Regenerative Medicine, Paracelsus Medical University, Salzburg, Austria.
Rodolphe PoupardinSpinal Cord Injury and Tissue Regeneration Center Salzburg, Paracelsus Medical University, Salzburg, Austria.ORCID 0000-0001-5195-5155
Anna HoogSpinal Cord Injury and Tissue Regeneration Center Salzburg, Paracelsus Medical University, Salzburg, Austria.ORCID 0000-0002-1518-651X
Daniela AsslaberIIIrd Medical Department with Hematology and Medical Oncology, Oncologic Center, Paracelsus Medical University, Salzburg, Austria.
Iris Karina GratzDepartment of Biosciences, University of Salzburg, Salzburg, Austria.ORCID 0000-0001-7470-7277
Heike MrowetzInstitute of Molecular Regenerative Medicine, Paracelsus Medical University, Salzburg, Austria.
Ariane BenedettiSpinal Cord Injury and Tissue Regeneration Center Salzburg, Paracelsus Medical University, Salzburg, Austria.
Diana Marisa Bessa de SousaInstitute of Molecular Regenerative Medicine, Paracelsus Medical University, Salzburg, Austria.
Richard GreilIIIrd Medical Department with Hematology and Medical Oncology, Oncologic Center, Paracelsus Medical University, Salzburg, Austria.
Alexander EgleIIIrd Medical Department with Hematology and Medical Oncology, Oncologic Center, Paracelsus Medical University, Salzburg, Austria.ORCID 0000-0003-0648-4416
David GateDepartment of Neurology and Neurological Sciences, Stanford University School of Medicine, Stanford, CA.
Tony Wyss-CorayDepartment of Neurology and Neurological Sciences, Stanford University School of Medicine, Stanford, CA.ORCID 0000-0001-5893-0831
Ludwig AignerInstitute of Molecular Regenerative Medicine, Paracelsus Medical University, Salzburg, Austria; ludwig.aigner@pmu.ac.at.
Paracelsus Medical University · ATUniversity of Salzburg · ATVA Palo Alto Health Care System · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Peripheral immune cell infiltration into the brain is a prominent feature in aging and various neurodegenerative diseases such as Alzheimer's disease (AD). As AD progresses, CD8

Indexed as

Alzheimer DiseaseAmyloid beta-Protein PrecursorAnimalsBrainCD8-Positive T-LymphocytesDisease Models, AnimalMemory T CellsMiceMice, Inbred C57BLMice, TransgenicPresenilin-1TranscriptomeAmyloid beta-Protein PrecursorPresenilin-1

Identifiers

PMID36165202
PMCPMC9515311
OpenAlexW4297248850

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.