Evidence map›Paper›PMID 36165197›Full record

ArticleJournal of immunology (Baltimore, Md. : 1950)2022

Negative Cross-Talk between TLR2/4-Independent AMPKα1 and TLR2/4-Dependent JNK Regulates

Shingo Matsuyama, Kensei Komatsu, Byung-Cheol Lee, Yukihiro Tasaki, Masanori Miyata, Haidong Xu, Tsuyoshi Shuto, Hirofumi Kai, Jian-Dong Li

Open access · bronzeAbstract read
In one paragraph

Article in Journal of immunology (Baltimore, Md. : 1950), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.3field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 5 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 3 countries.

Shingo MatsuyamaCenter for Inflammation, Immunity & Infection, Institute for Biomedical Sciences, Georgia State University, Atlanta, GA; and.
Kensei KomatsuCenter for Inflammation, Immunity & Infection, Institute for Biomedical Sciences, Georgia State University, Atlanta, GA; and.ORCID 0000-0001-7418-3805
Byung-Cheol LeeCenter for Inflammation, Immunity & Infection, Institute for Biomedical Sciences, Georgia State University, Atlanta, GA; and.
Yukihiro TasakiCenter for Inflammation, Immunity & Infection, Institute for Biomedical Sciences, Georgia State University, Atlanta, GA; and.
Masanori MiyataCenter for Inflammation, Immunity & Infection, Institute for Biomedical Sciences, Georgia State University, Atlanta, GA; and.
Haidong XuCenter for Inflammation, Immunity & Infection, Institute for Biomedical Sciences, Georgia State University, Atlanta, GA; and.
Tsuyoshi ShutoDepartment of Molecular Medicine, Graduate School of Pharmaceutical Sciences, Kumamoto University, Kumamoto, Japan.
Hirofumi KaiDepartment of Molecular Medicine, Graduate School of Pharmaceutical Sciences, Kumamoto University, Kumamoto, Japan.
Jian-Dong LiCenter for Inflammation, Immunity & Infection, Institute for Biomedical Sciences, Georgia State University, Atlanta, GA; and jdli@gsu.edu.ORCID 0000-0002-5593-050X
Georgia State University · USKumamoto University · JP

Funding

Development of innovative therapeutics for otitis mediaR01DC015557 · NIDCD · GEORGIA STATE UNIVERSITY · PI KOHANE, DANIEL S, LI, JIAN-DONG · 2018 to 2022
$2.9M
Novel regulation of mucosal innate defense by AMPK in Otitis MediaR01DC019512 · NIDCD · GEORGIA STATE UNIVERSITY · PI LI, JIAN-DONG · 2021 to 2025
$2.3M
Pathogenesis of pneumococcal otitis mediaR01DC013833 · NIDCD · GEORGIA STATE UNIVERSITY · PI LI, JIAN-DONG · 2015 to 2019
$1.6M
NIDCD NIH HHS R01 DC013833NIDCD NIH HHS R01 DC015557NIDCD NIH HHS R01 DC019512
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Otitis MediaStreptococcus pneumoniaeAMP-Activated Protein KinasesAnimalsBacterial ProteinsCalcium-Calmodulin-Dependent Protein Kinase KinaseCalmodulinCholesterolImmunity, InnateMiceStreptolysinsToll-Like Receptor 2AMP-Activated Protein KinasesBacterial ProteinsCalcium-Calmodulin-Dependent Protein Kinase KinaseCalmodulinCholesterolStreptolysinsTlr2 protein, mouseToll-Like Receptor 2

Identifiers

PMID36165197
PMCPMC9659420
OpenAlexW4297253552

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.