Evidence map›Paper›PMID 36165181›Full record

ArticleJournal of immunology (Baltimore, Md. : 1950)2022

IL-4-Induced Quiescence of Resting Naive B Cells Is Disrupted in Systemic Lupus Erythematosus.

Min Gao, Shanrun Liu, W Winn Chatham, John D Mountz, Hui-Chen Hsu

Open access · bronzeAbstract read
In one paragraph

Article in Journal of immunology (Baltimore, Md. : 1950), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
2.4field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 18 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. Review
  9. IL-4 alters TLR7-induced B cell developmental program in lupus.Clinical immunology (Orlando, Fla.) · 2025
    Article
  10. Review
  11. Article
  12. Review
  13. Article
  14. Article
  15. Article
  16. Review
  17. Increased development of T-betClinical immunology (Orlando, Fla.) · 2023
    Article
  18. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Min GaoUniversity of Alabama at Birmingham, Birmingham, AL; and.
Shanrun LiuUniversity of Alabama at Birmingham, Birmingham, AL; and.ORCID 0000-0002-7201-4212
W Winn ChathamUniversity of Alabama at Birmingham, Birmingham, AL; and.
John D MountzUniversity of Alabama at Birmingham, Birmingham, AL; and jdmountz@uabmc.edu hhsu@uabmc.edu.ORCID 0000-0001-9061-3158
Hui-Chen HsuUniversity of Alabama at Birmingham, Birmingham, AL; and jdmountz@uabmc.edu hhsu@uabmc.edu.ORCID 0000-0002-0317-5725
University of Alabama at Birmingham · US

Funding

Virology CoreP30AI027767 · NIAID · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI Latesha Ellen Elopre · 1988 to 2026
$84.1M
ROS Modulation of Innate and Adaptive Immunity in RAP30AR048311 · NIAMS · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI MOUNTZ, JOHN D · 2001 to 2017
$9.5M
B cell intrinsic interferon-beta regulates autoreactive B cell developmentR01AI134023 · NIAID · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI MOUNTZ, JOHN D · 2018 to 2022
$2.4M
Interferon Beta Initiated Development of Immunogenic T1 B cells in LupusI01BX004049 · VA · BIRMINGHAM VA MEDICAL CENTER · PI MOUNTZ, JOHN D · 2018 to 2022
–
B-cell innate and adaptive protective immunity to SARS-CoV-2I01BX005448 · VA · BIRMINGHAM VA MEDICAL CENTER · PI MOUNTZ, JOHN D · 2021 to 2023
–
BLRD VA I01 BX004049BLRD VA I01 BX005448NIAID NIH HHS P30 AI027767NIAID NIH HHS R01 AI134023NIAMS NIH HHS P30 AR048311
6 · The paper itself

Abstract

Activated naive (aNAV) B cells have been shown to be the precursor of the CD11c

Indexed as

B-Lymphocyte SubsetsLupus Erythematosus, SystemicAutoantibodiesHumansImmunoglobulin DInterleukin-4RNAAutoantibodiesImmunoglobulin DInterleukin-4RNA

Identifiers

PMID36165181
PMCPMC9741951
OpenAlexW4297261439

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.