Evidence map›Paper›PMID 36164704›Full record

ArticleDrug delivery2022

Synthesis of dual-stimuli responsive metal organic framework-coated iridium oxide nanocomposite functionalized with tumor targeting albumin-folate for synergistic photodynamic/photothermal cancer therapy.

Xiangtian Deng, Renliang Zhao, Qingcheng Song, Yiran Zhang, Haiyue Zhao, Hongzhi Hu, Zhen Zhang, Weijian Liu, Wei Lin, Guanglin Wang

Open access · goldAbstract read
In one paragraph

Article in Drug delivery, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
3.3field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 43 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 5 institutions in 1 country.

Xiangtian DengTrauma Medical Center, Department of Orthopedics Surgery, West China Hospital, Sichuan University, Chengdu, China.
Renliang ZhaoTrauma Medical Center, Department of Orthopedics Surgery, West China Hospital, Sichuan University, Chengdu, China.
Qingcheng SongDepartment of Orthopaedic Surgery, The Third Hospital of Hebei Medical University, Shijazhuang, China.
Yiran ZhangSchool of Medicine, Nankai University, Tianjin, China.
Haiyue ZhaoSchool of Medicine, Nankai University, Tianjin, China.
Hongzhi HuDepartment of Orthopaedics, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Zhen ZhangTrauma Medical Center, Department of Orthopedics Surgery, West China Hospital, Sichuan University, Chengdu, China.
Weijian LiuDepartment of Orthopaedics, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Wei LinDepartment of Gynecology, West China Second Hospital, Sichuan University, Chengdu, China.
Guanglin WangTrauma Medical Center, Department of Orthopedics Surgery, West China Hospital, Sichuan University, Chengdu, China.
Sichuan University · CNHuazhong University of Science and Technology · CNNankai University · CNThird Hospital of Hebei Medical University · CNWest China Second University Hospital of Sichuan University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The synergistic effects of photothermal therapy (PTT) and photodynamic therapy (PDT) has attracted considerable attention in the field of cancer therapy because of its excellent anti-tumor effect. This work provides a novel pH/NIR responsive therapeutic nanoplatform, IrO

Indexed as

Metal-Organic FrameworksNanocompositesNanoparticlesNeoplasmsPhotochemotherapyPhotosensitizing AgentsCatalaseCell Line, TumorFolic AcidHumansHydrogen PeroxideIridiumOxygenReactive Oxygen SpeciesSerum Albumin, BovineTriazenes1-phenyl-3,3-dimethyltriazeneCatalaseFolic AcidHydrogen PeroxideIridiumiridium oxideMetal-Organic FrameworksOxygenPhotosensitizing AgentsReactive Oxygen SpeciesSerum Albumin, BovineTriazenesdrug targetingIridium oxidemetal organic frameworkphotodynamic therapyphotothermal therapy

Identifiers

PMID36164704
PMCPMC9542428
OpenAlexW4297266236

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.