Evidence map›Paper›PMID 36164664›Full record

ArticleCanadian journal of gastroenterology & hepatology2022

Recipient Age Predicts 20-Year Survival in Pediatric Liver Transplant.

Stephanie Keeling, Malcolm F McDonald, Adrish Anand, Jordan Dunson, Elizabeth Williams, Theodore Zhang, Brian Hickner, Nhu Thao Nguyen Galván, Christine O' Mahony, John A Goss and 1 more

Abstract read
In one paragraph

Article in Canadian journal of gastroenterology & hepatology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Pediatric liver transplant outcomes: A comparative analysis of steatotic donor grafts.Journal of pediatric gastroenterology and nutrition · 2025
    Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Stephanie KeelingDepartment of Student Affairs, Baylor College of Medicine, Department of Medicine, Houston 77030, TX, USA.ORCID 0000-0002-4235-8276
Malcolm F McDonaldDepartment of Student Affairs, Baylor College of Medicine, Department of Medicine, Houston 77030, TX, USA.ORCID 0000-0002-2627-9754
Adrish AnandDepartment of Student Affairs, Baylor College of Medicine, Department of Medicine, Houston 77030, TX, USA.ORCID 0000-0002-6673-6251
Jordan DunsonDepartment of Student Affairs, Baylor College of Medicine, Department of Medicine, Houston 77030, TX, USA.
Elizabeth WilliamsDepartment of Student Affairs, Baylor College of Medicine, Department of Medicine, Houston 77030, TX, USA.
Theodore ZhangDepartment of Student Affairs, Baylor College of Medicine, Department of Medicine, Houston 77030, TX, USA.
Brian HicknerDepartment of Student Affairs, Baylor College of Medicine, Department of Medicine, Houston 77030, TX, USA.
Nhu Thao Nguyen GalvánDivision of Abdominal Transplant, Michael E DeBakey Department of Surgery, Baylor College of Medicine, Houston 77030, TX, USA.ORCID 0000-0002-1289-4692
Christine O' MahonyDivision of Abdominal Transplant, Michael E DeBakey Department of Surgery, Baylor College of Medicine, Houston 77030, TX, USA.
John A GossDivision of Abdominal Transplant, Michael E DeBakey Department of Surgery, Baylor College of Medicine, Houston 77030, TX, USA.
Abbas RanaDivision of Abdominal Transplant, Michael E DeBakey Department of Surgery, Baylor College of Medicine, Houston 77030, TX, USA.ORCID 0000-0003-2979-0598

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Pediatric liver transplant recipients have demonstrated excellent long-term survival. The purpose of this analysis is to investigate factors associated with 20-year survival to identify areas for improvement in patient care. Methods: Kaplan-Meier with log-rank test as well as univariate and multivariate logistic regression methods were used to retrospectively analyze 4,312 liver transplant recipients under the age of 18 between September 30, 1987 and March 9, 1998. Our primary endpoint was 20-year survival among one-year survival. Results: Logistic regression analysis identified recipient age as a significant risk factor, with recipients below 5 years old having a higher 20-year survival rate ( Conclusions: Our analysis suggests that long-term survival is inversely correlated with recipient age following pediatric liver transplant. If validated with further studies, this conclusion may have profound implications on the timing of pediatric liver transplantation.

Indexed as

Liver TransplantationChildChild, PreschoolGraft SurvivalHumansLiving DonorsRetrospective StudiesSurvival Rate

Identifiers

PMID36164664
PMCPMC9509270

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.