Evidence map›Paper›PMID 36164627›Full record

ArticleReports of biochemistry & molecular biology2022

The Effect of Fasting on Oxidative Stress in the Vital Organs of New Zealand White Rabbit.

Novi Silvia Hardiany, Adrian Prasetya Karman, Aisha Safa Putri Calista, Budi Gittanaya Anindyanari, Daniell Edward Rahardjo, Puti Retasya Novira, Rania Rifdah Taufiq, Shofiyya Imtiyaz, Radiana Dhewayani Antarianto

Open access · greenAbstract read
In one paragraph

Article in Reports of biochemistry & molecular biology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.3field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 11 citations in OpenAlex.

  1. Review
  2. Review
  3. Review
  4. Article
  5. Article
  6. Intermittent Metabolic Switching and Vascular Cognitive Impairment.Journal of obesity & metabolic syndrome · 2024
    Review
  7. Article
  8. Article
  9. Article
  10. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Novi Silvia HardianyDepartment of Biochemistry & Molecular Biology, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia.
Adrian Prasetya KarmanFaculty of Medicine Universitas Indonesia, Jakarta, Indonesia.
Aisha Safa Putri CalistaFaculty of Medicine Universitas Indonesia, Jakarta, Indonesia.
Budi Gittanaya AnindyanariFaculty of Medicine Universitas Indonesia, Jakarta, Indonesia.
Daniell Edward RahardjoFaculty of Medicine Universitas Indonesia, Jakarta, Indonesia.
Puti Retasya NoviraFaculty of Medicine Universitas Indonesia, Jakarta, Indonesia.
Rania Rifdah TaufiqFaculty of Medicine Universitas Indonesia, Jakarta, Indonesia.
Shofiyya ImtiyazFaculty of Medicine Universitas Indonesia, Jakarta, Indonesia.
Radiana Dhewayani AntariantoDepartment of Histology, Faculty of Medicine Universitas Indonesia, Jakarta, Indonesia.
University of Indonesia · ID

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Oxidative stress is defined as the condition in which balance between the synthesis and detoxification of reactive oxygen species in cells is disrupted. This research explored the effects of intermittent and prolonged fasting on malondialdehyde (MDA), carbonyl, reduced glutathione (GSH), and specific activity of catalase as biomarkers for oxidative stress in hearts, brains, and kidneys of New Zealand White (NZW) rabbits. Methods: Fifteen NZW rabbits were divided into control, intermittent fasting (IF), and prolonged fasting (PF) groups. The controls were fed ad lib. IF and PF groups were fasted for 16 and 40 hours, respectively, followed by eight hours of non-fasting, for six days and were sacrificed on the 7 Results: In heart, MDA was significantly greater in the control than in the IF and PF groups. In brain, GSH was greater in the IF than in the PF and control groups. Also, in brain, catalase specific activity was significantly greater in the control than in the IF and PF groups. In kidney, catalase specific activity was significantly less in the PF than in the control group. Conclusion: The effect of fasting on oxidative stress in various organs showed various responses, however fasting reduced oxidative stress based on MDA and GSH levels in the heart and brain, respectively.

Indexed as

FastingOxidative stressRabbitVital organs

Identifiers

PMID36164627
PMCPMC9455196
OpenAlexW4297257113

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.