Evidence map›Paper›PMID 36164594›Full record

ArticleAPL bioengineering2022

Immune checkpoint blockade enhances chemophototherapy in a syngeneic pancreatic tumor model.

Sanjana Ghosh, Xuedan He, Wei-Chiao Huang, Jonathan F Lovell

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in APL bioengineering, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Drug/gene delivery and theranostics.APL bioengineering · 2023
    Article
  5. Review
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Sanjana GhoshDepartment of Biomedical Engineering, University at Buffalo, State University of New York, Buffalo, New York 14260, USA.
Xuedan HeDepartment of Biomedical Engineering, University at Buffalo, State University of New York, Buffalo, New York 14260, USA.
Wei-Chiao HuangDepartment of Biomedical Engineering, University at Buffalo, State University of New York, Buffalo, New York 14260, USA.
Jonathan F LovellDepartment of Biomedical Engineering, University at Buffalo, State University of New York, Buffalo, New York 14260, USA.ORCID https://orcid.org/0000-0002-9052-884X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Pancreatic cancer (PaCa) suffers from poor treatment options for locally advanced cases. Chemophototherapy (CPT) is an emerging anti-tumor modality, and porphyrin-phospholipid liposomes have been shown to be versatile drug carriers for CPT in preclinical rodent models. Here we show that in the syngeneic subcutaneous KPC PaCa tumor model, exhausted CD8

Identifiers

PMID36164594
PMCPMC9509203

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.