Evidence map›Paper›PMID 36164551›Full record

ArticleInternational journal of pharmaceutics: X2022

Biological activity of gold nanoparticles combined with the NFL-TBS.40-63 peptide, or with other cell penetrating peptides, on rat glioblastoma cells.

A Griveau, C Arib, J Spadavecchia, J Eyer

Erratum issuedAbstract read
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In one paragraph

Article in International journal of pharmaceutics: X, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Nanotherapy of Glioblastoma-Where Hope Grows.International journal of molecular sciences · 2025
    Review
  3. Review
  4. Review
  5. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

4 authors.

A GriveauUniv Angers, Inserm, CNRS, MINT, SFR ICAT, F-49000 Angers, France.
C AribCNRS, UMR 7244, CSPBAT, Laboratoire de Chimie, Structures et Propriétés de Biomatériaux Et D'Agents Thérapeutiques Université Paris 13, Sorbonne Paris Cité, Bobigny, France.
J SpadavecchiaCNRS, UMR 7244, CSPBAT, Laboratoire de Chimie, Structures et Propriétés de Biomatériaux Et D'Agents Thérapeutiques Université Paris 13, Sorbonne Paris Cité, Bobigny, France.
J EyerUniv Angers, Inserm, CNRS, MINT, SFR ICAT, F-49000 Angers, France.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Targeting, detecting, and destroying selectively cancer cells or specific organelles is a major challenge of nanomedicine. Recently, a new methodology was conceived to synthesize gold nanoparticles combined with a peptide having a C-terminal biotin (BIOT-NFL-peptide). This methodology called "Method IN" allows specific interactions between the BIOT-NFL-peptide, the polyethylene glycol diacid (PEG-COOH) and the gold salt (Au III) to produce multifunctional hybrid nano-carriers called BIOT-NFL-PEG-AuNPs. Here, we show that it is possible to use this strategy to synthesize multifunctional hybrid nano-carriers with other cell-penetrating peptides including TAT and Vim-peptides.

Indexed as

AuNPs, Gold nanoparticlesBIOT-CPP-PEG-AuNPs, Biotinylated cell-penetrating peptides polyethylene glycol gold nanoparticlesBIOT-NFL-PEG-AuNPs, Biotinylated NFL-peptide polyethylene glycol gold nanoparticlesBIOT-NFL-peptideBIOT-TAT-PEG-AuNPs, Biotinylated TAT-peptide polyethylene glycol gold nanoparticlesBIOT-TAT-peptideBIOT-Vim-PEG-AuNPs, Biotinylated Vim-peptide polyethylene glycol gold nanoparticlesBIOT-Vim-peptideCPP, Cell-penetrating peptidesGBM, GlioblastomaGold nanoparticlesNFL-peptide, NFL-TBS.40-63, or Neuro Filament Low subunit Tubulin Binding Site 40-63PEG-AuNPs, Polyethylene glycol gold nanoparticlesRat glioblastoma cellsTBS, Tubulin Binding SitesTEM, Transmission electron microscopyTransmission electron microscopyVim-peptide, Vim-TBS.58-81, or Vimentin Tubulin Binding Site 58-81

Identifiers

PMID36164551
PMCPMC9508353

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.