Evidence map›Paper›PMID 36164504›Full record

ReviewMaterials today. Bio2022

Design strategies for adhesive hydrogels with natural antibacterial agents as wound dressings: Status and trends.

Hang Yao, Ming Wu, Liwei Lin, Zhonglian Wu, Minjun Bae, Sumin Park, Shuli Wang, Wang Zhang, Jiefeng Gao, Dongan Wang and 1 more

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Materials today. Bio, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

30 citing papers in PubMed.

  1. Article
  2. [Functional requirements and research advances of antimicrobial hydrogels for combat trauma wound repair].Sheng wu yi xue gong cheng xue za zhi = Journal of biomedical engineering = Shengwu yixue gongchengxue zazhi · 2026
    Review
  3. Advances in carrier-free nanodrug delivery systems.Drug delivery and translational research · 2026
    Review
  4. Article
  5. Recent Advances in Multi-Functional Hydrogels.Gels (Basel, Switzerland) · 2026
    Article
  6. Article
  7. Review
  8. Article
  9. Review
  10. Article
  11. Review
  12. Article
  13. Review
  14. Article
  15. Article
  16. Article
  17. Article
  18. Review
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Hang YaoSchool of Chemistry and Chemical Engineering, Yangzhou University, Yangzhou, Jiangsu, 225002, PR China.
Ming WuSchool of Chemistry and Chemical Engineering, Yangzhou University, Yangzhou, Jiangsu, 225002, PR China.
Liwei LinDepartment of Applied Bioengineering, Graduate School of Convergence Science and Technology, Seoul National University, Seoul, 08826, Republic of Korea.
Zhonglian WuSchool of Chemistry and Chemical Engineering, Yangzhou University, Yangzhou, Jiangsu, 225002, PR China.
Minjun BaeDepartment of Applied Bioengineering, Graduate School of Convergence Science and Technology, Seoul National University, Seoul, 08826, Republic of Korea.
Sumin ParkDepartment of Applied Bioengineering, Graduate School of Convergence Science and Technology, Seoul National University, Seoul, 08826, Republic of Korea.
Shuli WangFujian Engineering Research Center for Solid-State Lighting, Department of Electronic Science, School of Electronic Science and Engineering, Xiamen University, Xiamen, Fujian, 361005, PR China.
Wang ZhangSchool of Chemistry and Chemical Engineering, Yangzhou University, Yangzhou, Jiangsu, 225002, PR China.
Jiefeng GaoSchool of Chemistry and Chemical Engineering, Yangzhou University, Yangzhou, Jiangsu, 225002, PR China.
Dongan WangDepartment of Biomedical Engineering, City University of Hong Kong, Kowloon Tong, Hong Kong SAR, 999077, PR China.
Yuanzhe PiaoDepartment of Applied Bioengineering, Graduate School of Convergence Science and Technology, Seoul National University, Seoul, 08826, Republic of Korea.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The wound healing process is usually susceptible to different bacterial infections due to the complex physiological environment, which significantly impairs wound healing. The topical application of antibiotics is not desirable for wound healing because the excessive use of antibiotics might cause bacteria to develop resistance and even the production of super bacteria, posing significant harm to human well-being. Wound dressings based on adhesive, biocompatible, and multi-functional hydrogels with natural antibacterial agents have been widely recognized as effective wound treatments. Hydrogels, which are three-dimensional (3D) polymer networks cross-linked through physical interactions or covalent bonds, are promising for topical antibacterial applications because of their excellent adhesion, antibacterial properties, and biocompatibility. To further improve the healing performance of hydrogels, various modification methods have been developed with superior biocompatibility, antibacterial activity, mechanical properties, and wound repair capabilities. This review summarizes hundreds of typical studies on various ingredients, preparation methods, antibacterial mechanisms, and internal antibacterial factors to understand adhesive hydrogels with natural antibacterial agents for wound dressings. Additionally, we provide prospects for adhesive and antibacterial hydrogels in biomedical applications and clinical research.

Indexed as

Adhesive hydrogelsAntibacterial agentsWound dressingsWound healing

Identifiers

PMID36164504
PMCPMC9508611

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.