SynthesisClinical endocrinology2022
The prevalence of acromegaly is higher than previously reported: Changes over a three-decade period.
Synthesis in Clinical endocrinology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 5 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
23 citing papers in PubMed, 5 syntheses or guidelines pooled it.
- Efficacy and safety of pharmacologic therapies in acromegaly: a systematic literature review and network meta-analysis.The Journal of clinical endocrinology and metabolism · 2026Pooled it
- Psychiatric morbidity in acromegaly: a cohort study and meta-analysis of the literature.Pituitary · 2025Pooled it
- Anxiety, depression and acromegaly: a systematic review.Journal of endocrinological investigation · 2025Pooled it
- Uterine fibroids in women diagnosed with acromegaly: a systematic review.Reviews in endocrine & metabolic disorders · 2024Pooled it
- The prevalence of acromegaly is higher than previously reported: Changes over a three-decade period.Clinical endocrinology · 2022Pooled it
- Acromegaly is associated with an increased incidence of primary malignant tumors: data from a national study in Sweden.The Journal of clinical endocrinology and metabolism · 2026Article
- Bone and joint quality remains impaired in long-term controlled acromegaly: an HR-pQCT study.Journal of the Endocrine Society · 2026Article
- Endoscopic resection of knosp grade 0-2 growth hormone-secreting pituitary adenomas with routine medial cavernous sinus wall excision.Acta neurochirurgica · 2026Article
- Changing understanding of acromegaly epidemiology and early mortality risk.The Journal of clinical endocrinology and metabolism · 2026Review
- Osteometabolic complications in patients with secreting pituitary adenomas: Is there an impact of gender?Pituitary · 2026Review
- Reevaluating the Need for Routine IGF-1 Screening in Poorly Controlled Type 2 Diabetes Mellitus.Endocrinology, diabetes & metabolism · 2026Article
- Hypersomatotropism without concurrent diabetes mellitus in cats: 28 cases (2014-2024).Journal of veterinary internal medicine · 2026Article
- Outcome of acromegalic patients undergoing endoscopic endonasal surgery: collaborative French and Italian cohort, a 25-year experience.Neurosurgical review · 2025Article
- Healthcare utilization and costs among patients with acromegaly in the United States.Journal of comparative effectiveness research · 2025Article
- Anatomical considerations in acromegalic patients: A multicentric cohort study.Surgical neurology international · 2025Article
- Ends of the spectrum best practices for early detection and multidisciplinary management of acromegaly.Journal of neuro-oncology · 2025Review
- Cost-effectiveness analysis of second-line medical therapies in acromegaly: a real-life study.Frontiers in endocrinology · 2025Article
- GIGANTISM AND ACROMEGALY THROUGH HISTORY.Acta clinica Croatica · 2024Review
- The changing landscape of acromegaly - an epidemiological perspective.Reviews in endocrine & metabolic disorders · 2024Review
- Establishing a valid cohort of patients with acromegaly by combining the National Patient Register with the Swedish Pituitary Register.Journal of endocrinological investigation · 2024Review
Corrections and comments
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Authors and funding
10 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveTo study time-related changes in the prevalence and patient characteristics of acromegaly, as well as to assess the impact of changes in treatment on disease control.
methodsA total of 107 patients with acromegaly were identified by healthcare registries and subsequently validated by patient chart review over a three-decade period (1992-2021). A systematic literature review focusing on the incidence and prevalence of acromegaly was performed identifying 31 studies.
resultsThe prevalence of acromegaly significantly increased throughout the study period (R
conclusionThe prevalence of acromegaly is higher than previously reported and the clinical presentation has shifted towards a milder phenotype. Modern treatment of acromegaly enables individualized treatment and disease control in the majority of patients.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.