Evidence map›Paper›PMID 36163604›Full record

ArticleAIDS and behavior2023

The Association Between Objectively-Measured Physical Activity and Cognitive Functioning in Middle-Aged and Older People Living with HIV.

Pariya L Fazeli, Amanda L Willig, Vitor Oliveira, Thomas W Buford, David E Vance, Greer Burkholder, Heidi M Crane, Christine Horvat Davey, Julia Fleming, Allison R Webel

Open access · greenAbstract read
In one paragraph

Article in AIDS and behavior, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
3.1field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 13 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 5 institutions in 1 country.

Pariya L FazeliSchool of Nursing, University of Alabama at Birmingham, Birmingham, USA. plfazeli@uab.edu.ORCID http://orcid.org/0000-0001-6629-0010
Amanda L WilligSchool of Medicine, University of Alabama at Birmingham, Birmingham, USA.
Vitor OliveiraSchool of Nursing, University of Washington, Seattle, USA.
Thomas W BufordSchool of Medicine, University of Alabama at Birmingham, Birmingham, USA.
David E VanceSchool of Nursing, University of Alabama at Birmingham, Birmingham, USA.
Greer BurkholderSchool of Medicine, University of Alabama at Birmingham, Birmingham, USA.
Heidi M CraneDepartment of Medicine, University of Washington, Seattle, USA.
Christine Horvat DaveyFrances Payne Bolton School of Nursing, Case Western Reserve University, Cleveland, USA.
Julia FlemingFenway Health, Boston, USA.
Allison R WebelSchool of Nursing, University of Washington, Seattle, USA.
University of Alabama at Birmingham · USUniversity of Washington · USCase Western Reserve University · USFenway Health · USUniversity of Alabama at Birmingham Hospital · US

Funding

Unsolicited R24 for the CFAR-Network of Integrated Clinical Sciences, CNICSR24AI067039 · NIAID · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI Michael S. Saag · 2006 to 2026
$99.4M
HIV and Aging Research Consortium (HARC)R33AG067069 · NIA · UNIVERSITY OF WASHINGTON · PI STEVEN N. AUSTAD, Heidi M. Crane · 2020 to 2026
$4.8M
Impact of Physical Activity Routines and Dietary Intake on the Longitudinal Symptom Experience of the people living with HIV (PROSPER-HIV)R01NR018391 · NINR · UNIVERSITY OF WASHINGTON · PI WEBEL, ALLISON R · 2018 to 2022
$4.0M
Interconnections among Cognition, Pain, and Physical Function in Aging.K02AG062498 · NIA · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI BUFORD, THOMAS W · 2020 to 2024
$524k
NIAID NIH HHS R24 AI067039NIA NIH HHS K02 AG062498NIA NIH HHS R33 AG067069NIH HHS 3R01-NR018391-02S2NINR NIH HHS R01 NR018391
6 · The paper itself

Abstract

Middle-aged and older people living with HIV (PWH) are at higher risk for cognitive impairment and engage in lower levels of physical activity (PA) than seronegative counterparts. Research examining the association between objectively-measured PA and cognitive function in this population is scarce. This cross-sectional study examined the association between accelerometry-measured PA and cognitive functioning among 75 PWH (mean age 55.63). Light PA was the PA variable with the most consistent associations with cognition, with more minutes per week of light PA (performed in bouts of ≥ 10 min) being associated with better executive function, working memory/attention, and speed of processing performance, adjusted for age and current CD4 count. Findings suggest that although middle-aged and older PWH engage in more light than moderate-to-vigorous PA, light PA may be beneficial to cognition. Longitudinal studies are needed to understand PA dose-response associations with cognitive trajectories, cognitive domain specificity of PA effects, and underlying neural mechanisms of PA.

Indexed as

HIV InfectionsAgedCognitionCross-Sectional StudiesExecutive FunctionExerciseHumansMiddle AgedAIDSBrain healthCognitive impairmentExerciseWalking

Identifiers

PMID36163604
PMCPMC10129017
OpenAlexW4297104702

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.