Evidence map›Paper›PMID 36163594›Full record

ArticleRheumatology international2023

Management of chronic rheumatic diseases in women 18-45 years of age in Asia Pacific: insights from patient and clinician surveys.

Yoshiya Tanaka, Claire Barrett, Yuji Hirano, Kei Ikeda, Kathy Paizis, Azusa Sameshima, Irina Mountian, Priscilla C Wong

Open access · hybridAbstract read
In one paragraph

Article in Rheumatology international, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.8field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 5 citations in OpenAlex.

  1. Review
  2. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 8 institutions in 4 countries.

Yoshiya TanakaUniversity of Occupational and Environmental Health, Japan, Kitakyushu, Japan. tanaka@med.uoeh-u.ac.jp.ORCID 0000-0002-0807-7139
Claire BarrettRedcliffe Hospital, Redcliffe and University of Queensland, St Lucia, Australia.ORCID 0000-0002-0362-0382
Yuji HiranoToyohashi Municipal Hospital, Toyohashi, Japan.ORCID 0000-0002-0422-8139
Kei IkedaChiba University Hospital, Chiba, Japan.ORCID 0000-0003-0574-9611
Kathy PaizisAustin Health, and Mercy Hospital for Women, Heidelberg, and Western Health, St Albans, Australia.ORCID 0000-0002-3580-1970
Azusa SameshimaUniversity of Toyama, Toyama, Japan.ORCID 0000-0002-8087-6066
Irina MountianUCB Pharma, Brussels, Belgium.ORCID 0000-0002-1510-6428
Priscilla C WongThe Chinese University of Hong Kong, Hong Kong, HK, Hong Kong.ORCID 0000-0001-8713-9539
Chiba University Hospital · JPChinese University of Hong Kong · HKMercy Hospital for Women · AUThe University of Queensland · AUToyohashi Municipal Hospital · JPUCB Pharma (Belgium) · BEUniversity of Occupational and Environmental Health Japan · JPUniversity of Toyama · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivePerspectives of women aged 18-45 years with chronic rheumatic diseases (CRD), and clinicians, in the Asia-Pacific (APAC) region are reported.

methodsOnline surveys were completed by women, pregnant in the past 2-5 years, with moderate to severe rheumatoid arthritis (RA), psoriatic arthritis (PsA), axial spondyloarthritis (axSpA), and rheumatologists, obstetricians, orthopaedic surgeons who medically manage CRDs.

resultsAmong 210 (RA 122, PsA 48, axSpA 40) patients, 52% (n = 109/210) delayed their decision to have children, most commonly due to concerns of passing on disease to offspring. 33% (n = 70/210) discussed family planning with a healthcare professional at diagnosis. Patients most often initiated discussions. 94% (n = 193/205) stopped treatment around pregnancy due to fear of fetal harm. 66% (n = 139/210) of patients felt they did not receive all relevant information on the impact of CRDs and treatment on pregnancy. Among 335 clinicians who participated, 82% (n = 143/174) of rheumatologists, 86% (n = 72/84) of obstetricians and 43% (n = 33/77) of orthopaedic surgeons agreed good disease control during pregnancy was their primary goal. 69% (n = 120/174) of rheumatologists were 'very comfortable' with prescribing tumour necrosis factor inhibitors (TNFi) for women aged 18-45 years. Comfort levels generally decreased with the onset of family planning. More obstetricians and orthopaedic surgeons supported avoiding TNFi during pregnancy than rheumatologists (40% [n = 34/84]/38% [n = 29/77] versus 16% [n = 28/174]). Access to more TNFi safety data during pregnancy was considered paramount for increasing clinician comfort.

conclusionsPatients and physicians need current information and multidisciplinary discussions for improved management of CRD in women in APAC.

Indexed as

Arthritis, PsoriaticArthritis, RheumatoidAdolescentAdultAsiaChildChronic DiseaseFemaleHumansMiddle AgedPregnancySurveys and QuestionnairesTumor Necrosis Factor InhibitorsYoung AdultTumor Necrosis Factor InhibitorsChronic rheumatic diseasesFamily planningPatientsPregnancySurveyTumour necrosis factor inhibitors

Identifiers

PMID36163594
PMCPMC9995525
OpenAlexW4297263542

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.