Evidence map›Paper›PMID 36163556›Full record

SynthesisEuropean archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery2023

Aetiology and management options for secondary referred otalgia: a systematic review and meta-analyses.

Munira Ally, Ahmad Moinie, Joan Lomas, Daniele Borsetto, George Mochloulis, Manohar Bance, Paolo Boscolo-Rizzo, Ananth Vijendren

Abstract readMeta-AnalysisSystematic Review
PubMed Publisher
In one paragraph

Synthesis in European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Nervus Intermedius Neuralgia.Current pain and headache reports · 2025
    Review
  2. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

8 authors.

Munira AllyENT Department, Lister Hospital, East and North Herts NHS Trust, Stevenage, SG1 4AB, Hertfordshire, UK.ORCID http://orcid.org/0000-0001-7911-9730
Ahmad MoinieENT Department, Lister Hospital, East and North Herts NHS Trust, Stevenage, SG1 4AB, Hertfordshire, UK.ORCID http://orcid.org/0000-0002-4512-0562
Joan LomasLister Education Centre, Lister Hospital, East and North Herts NHS Trust, Stevenage, SG1 4AB, UK.
Daniele BorsettoDepartment of ENT, Addenbrookes Hospital, Cambridge University Hospitals NHS Foundation Trust, Cambridge, UK.ORCID http://orcid.org/0000-0003-3464-2688
George MochloulisENT Department, Lister Hospital, East and North Herts NHS Trust, Stevenage, SG1 4AB, Hertfordshire, UK.
Manohar BanceDepartment of ENT, Addenbrookes Hospital, Cambridge University Hospitals NHS Foundation Trust, Cambridge, UK.ORCID http://orcid.org/0000-0001-8050-3617
Paolo Boscolo-RizzoDepartment of Medical, Surgical and Health Sciences, Section of Otolaryngology, University of Trieste, Trieste, Italy.ORCID http://orcid.org/0000-0002-4635-7959
Ananth VijendrenENT Department, Lister Hospital, East and North Herts NHS Trust, Stevenage, SG1 4AB, Hertfordshire, UK. ananth.vijendren1@nhs.net.ORCID http://orcid.org/0000-0002-9471-8878

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectives of reviewTo review the literature for the evidence base for the aetiology and management of referred otalgia, looking particularly at non-malignant, neuralgic, structural and functional issues. TYPE OF REVIEW: Systematic review. SEARCH STRATEGY: A systematic literature search was undertaken from the databases of EMBASE, CINAHL, MEDLINE®, BNI, and Cochrane Library according to predefined inclusion and exclusion criteria. EVALUATION

methodAll relevant titles, abstracts and full text articles were reviewed by three authors who resolved any differences by discussion and consultation with senior author.

results44 articles were included in our review. The overall quality of evidence was low, with the vast majority of the studies being case-series with three cohort and four randomised-controlled trials included. The prime causes and management strategies were focussed on temporomandibular joint dysfunction (TMJD), Eagle syndrome and neuralgia. Our meta-analyses found no difference on the management strategies for the interventions found.

conclusionsReferred otalgia is common and treatment should be aimed at the underlying pathology. Potential aetiologies are vast given the extensive sensory innervation of the ear. An understanding of this and a structured approach to patient assessment is important for optimal patient management.

Indexed as

EaracheCausalityHumansAdultEarEaracheOtalgiaPainReferred

Identifiers

PMID36163556

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.