Evidence map›Paper›PMID 36163164›Full record

SynthesisRespiratory investigation2023

Complications of a lung biopsy for severe respiratory failure: A systematic review and meta-analysis.

Hiroshi Sugimoto, Yosuke Fukuda, Yoshie Yamada, Hiroyuki Ito, Takeshi Tanaka, Takuo Yoshida, Satoshi Okamori, Koichi Ando, Yohei Okada

Abstract readMeta-AnalysisSystematic Review
In one paragraph

Synthesis in Respiratory investigation, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Hiroshi SugimotoDepartment of Respiratory Medicine, Kobe Red Cross Hospital, Hyogo, Japan. Electronic address: dr.sugimoto@gmail.com.
Yosuke FukudaDivision of Respiratory Medicine and Allergology, Department of Medicine, Showa University School of Medicine, Tokyo, Japan.
Yoshie YamadaDepartment of Healthcare Epidemiology, School of Public Health in the Graduate School of Medicine, Kyoto University, Kyoto, Japan.
Hiroyuki ItoDepartment of Pulmonology, Kameda Medical Center, Chiba, Japan.
Takeshi TanakaInfection Control and Education Center, Nagasaki University Hospital, Nagasaki, Japan.
Takuo YoshidaIntensive Care Unit, Department of Anesthesiology, Jikei University School of Medicine, Tokyo, Japan.
Satoshi OkamoriDepartment of Medicine, Division of Pulmonary Medicine, Keio University School of Medicine, Tokyo, Japan.
Koichi AndoDivision of Respiratory Medicine and Allergology, Department of Medicine, Showa University School of Medicine, Tokyo, Japan.
Yohei OkadaDepartment of Primary Care and Emergency Medicine, Graduate School of Medicine, Kyoto University, Kyoto, Japan; Preventive Services, School of Public Health, Kyoto University, Kyoto, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThis systematic review and meta-analysis aimed to evaluate the complications of lung biopsy in patients with acute respiratory failure (ARF), including acute respiratory distress syndrome (ARDS).

methodsWe searched the MEDLINE and Cochrane Central Register of Controlled Trials. The primary outcomes were biopsy-related death, respiratory failure, cardiac complications, bleeding, and other major complications. We used the McMaster Quality Assessment Scale of Harms (McHarm) to evaluate the risk of bias. A random-effects model was used to calculate the pooled frequencies.

resultsThirteen studies (consisting of 574 patients) were included in the meta-analysis. Furthermore, most of the included studies had a high or unclear risk of bias in half of the items in McHarm. All included studies evaluated surgical lung biopsies. The median overall hospital mortality was 53% (range: 17%-90%). The pooled frequencies of biopsy-related death, respiratory failure, cardiac complication, bleeding, and other major complications were 0.00% (95% confidence interval [CI]: 0.00%-0.21%), 1.30% (95% CI: 0.00%-5.69%), 1.03% (95% CI: 0.00%-3.73%), 1.46% (95% CI: 0.16%-3.56%), and 4.26% (95% CI: 0.00%-13.0%), respectively.

conclusionsThe results of this study will be valuable information in considering the indications of lung biopsy in patients with ARF, including ARDS.

trial registrationThe protocol was registered with the University Hospital Medical Information Network Clinical Trials Registry (UMIN 000040650).

Indexed as

Respiratory Distress SyndromeRespiratory InsufficiencyBiopsyHospital MortalityHumansLungAcute respiratory distress syndrome (ARDS)Acute respiratory failureComplicationsLung biopsy

Identifiers

PMID36163164
PMCPMC9501621

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.