Evidence map›Paper›PMID 36163104›Full record

ArticleTrends in parasitology2022

Housebreaking Plasmodium parasites leave their fingerprints at the door.

Lara Bardtke, Ian A Cockburn

Abstract readComment
PubMed Publisher
In one paragraph

Article in Trends in parasitology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors.

Lara BardtkeCharité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Department of Infectious Diseases and Respiratory Medicine, Augustenburger Platz 1, 13353 Berlin, Germany; Division of Immunology and Infectious Disease, John Curtin School of Medical Research, Australian National University, Canberra, ACT, 2601, Australia.
Ian A CockburnDivision of Immunology and Infectious Disease, John Curtin School of Medical Research, Australian National University, Canberra, ACT, 2601, Australia. Electronic address: ian.cockburn@anu.edu.au.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Protective antibodies against Plasmodium falciparum merozoite antigens, including EBA-175, can inhibit erythrocyte invasion. New data from Musasia et al. indicate that these antibodies can also trigger antibody-dependent phagocytosis of ring-infected and uninfected erythrocytes and that this correlates with protection from malaria. This provides a new pathway for vaccine design.

Indexed as

Malaria, FalciparumMalaria VaccinesParasitesAnimalsAntibodies, ProtozoanAntigens, ProtozoanErythrocytesPlasmodium falciparumProtozoan ProteinsAntibodies, ProtozoanAntigens, ProtozoanMalaria VaccinesProtozoan Proteinsblood stagescytophilic antibodiesEBA-175malariaphagocytosisPlasmodium

Identifiers

PMID36163104

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.