Evidence map›Paper›PMID 36162995›Full record

ArticleBMC psychiatry2022

Building a neurocognitive profile of suicidal risk in severe mental disorders.

Anna Comparelli, Valentina Corigliano, Benedetta Montalbani, Adele Nardella, Antonella De Carolis, Lorenzo Stampatore, Paride Bargagna, Francesca Forcina, Dorian Lamis, Maurizio Pompili

Registry-linked trialOpen access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in BMC psychiatry, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07688798 (Mentalization and Social Cognition in Adolescents After Suicide Attempt), which is not on this map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.3field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07688798 nanot yet recruitingnot on this mapstarted 2026, after this paper: background citation

Mentalization and Social Cognition in Adolescents After Suicide Attempt

TypeinterventionalSponsorAssistance Publique - Hôpitaux de ParisRan2026 to 2028Enrolled82ConditionsViolent Suicide Attempts in AdolescentsArmsTest, Questionnaires
3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 7 citations in OpenAlex.

  1. Social Cognition in Suicidal Behavior in Psychosis: A Systematic Review.Behavioral sciences (Basel, Switzerland) · 2025
    Review
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 2 countries.

Anna ComparelliAzienda Ospedaliero-Universitaria Sant'Andrea, Sapienza University of Rome, Via di Grottarossa 1035, Rome, Italy. anna.comparelli@uniroma1.it.
Valentina CoriglianoDepartment of Psychiatry Roma 1, Rome, Italy.
Benedetta MontalbaniPsychiatry Residency Training Program, Faculty of Medicine and Psychology, Sapienza University of Rome, Rome, Italy.
Adele NardellaDepartment of Psychiatry and Substance Abuse, Modena, Italy.
Antonella De CarolisDepartment of Neurosciences, Unit of Neurology, Mental Health and Sensory Organs, Sant'Andrea Hospital, Sapienza University, 00185, Rome, Italy.
Lorenzo StampatorePsychiatry Residency Training Program, Faculty of Medicine and Psychology, Sapienza University of Rome, Rome, Italy.
Paride BargagnaPsychiatry Residency Training Program, Faculty of Medicine and Psychology, Sapienza University of Rome, Rome, Italy.
Francesca ForcinaPsychiatry Residency Training Program, Faculty of Medicine and Psychology, Sapienza University of Rome, Rome, Italy.
Dorian LamisDepartment of Psychiatry and Behavioral Sciences, Emory University School of Medicine, Atlanta, GA, USA.
Maurizio PompiliAzienda Ospedaliero-Universitaria Sant'Andrea, Sapienza University of Rome, Via di Grottarossa 1035, Rome, Italy.
Sapienza University of Rome · ITAzienda Ospedaliera Sant'Andrea · ITEmory University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundResearch on the influence of neurocognitive factors on suicide risk, regardless of the diagnosis, is inconsistent. Recently, suicide risk studies propose applying a trans-diagnostic framework in line with the launch of the Research Domain Criteria Cognitive Systems model. In the present study, we highlight the extent of cognitive impairment using a standardized battery in a psychiatric sample stratified for different degrees of suicidal risk. We also differentiate in our sample various neurocognitive profiles associated with different levels of risk. MATERIALS AND

methodsWe divided a sample of 106 subjects into three groups stratified by suicide risk level: Suicide Attempt (SA), Suicidal Ideation (SI), Patient Controls (PC) and Healthy Controls (HC). We conducted a multivariate Analysis of Variance (MANOVA) for each cognitive domain measured through the standardized battery MATRICS Consensus Cognitive Battery (MCCB).

resultsWe found that the group of patients performed worse than the group of healthy controls on most domains; social cognition was impaired in the suicide risk groups compared both to HC and PC. Patients in the SA group performed worse than those in the SI group.

conclusionSocial cognition impairment may play a crucial role in suicidality among individuals diagnosed with serious mental illness as it is involved in both SI and SA; noteworthy, it is more compromised in the SA group fitting as a marker of risk severity.

Indexed as

Cognitive DysfunctionSuicidal IdeationHumansNeuropsychological TestsPsychiatric Status Rating ScalesSuicide, AttemptedMATRICS Consensus Cognitive BatteryNeurocognitionSocial cognitionSuicide attemptSuicide ideation

Identifiers

PMID36162995
PMCPMC9511976
OpenAlexW4297222952

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.