Evidence map›Paper›PMID 36162975›Full record

SynthesisEvidence-based mental health2022

Risk factors for suicide in adults: systematic review and meta-analysis of psychological autopsy studies.

Louis Favril, Rongqin Yu, Abdo Uyar, Michael Sharpe, Seena Fazel

Abstract readMeta-AnalysisSystematic Review
PubMed Full text at PMC Publisher
In one paragraph

Synthesis in Evidence-based mental health, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 155 papers, 14 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
155citing papers in PubMed, 14 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

155 citing papers in PubMed, 14 syntheses or guidelines pooled it.

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  19. Suicide mortality among survivors of first primary thyroid cancer: a population-based competing risk analysis.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2026
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95 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Louis Favril *Faculty of Law and Criminology, Ghent University, Ghent, Belgium.ORCID 0000-0002-9519-7824
Rongqin Yu *Department of Psychiatry, University of Oxford, Oxford, UK.
Abdo UyarDepartment of Psychiatry, University of Oxford, Oxford, UK.
Michael SharpeDepartment of Psychiatry, University of Oxford, Oxford, UK.
Seena FazelDepartment of Psychiatry, University of Oxford, Oxford, UK seena.fazel@psych.ox.ac.uk.

Funding

Wellcome Trust 202836/Z/16/Z
6 · The paper itself

Abstract

questionEffective prevention of suicide requires a comprehensive understanding of risk factors. STUDY SELECTION AND ANALYSIS: Five databases were systematically searched to identify psychological autopsy studies (published up to February 2022) that reported on risk factors for suicide mortality among adults in the general population. Effect sizes were pooled as odds ratios (ORs) using random-effects models for each risk factor examined in at least three independent samples.

findingsA total of 37 case-control studies from 23 countries were included, providing data on 40 risk factors in 5633 cases and 7101 controls. The magnitude of effect sizes varied substantially both between and within risk factor domains. Clinical factors had the strongest associations with suicide, including any mental disorder (OR=13.1, 95% CI 9.9 to 17.4) and a history of self-harm (OR=10.1, 95% CI 6.6 to 15.6). By comparison, effect sizes were smaller for other domains relating to sociodemographic status, family history, and adverse life events (OR range 2-5).

conclusionsA wide range of predisposing and precipitating factors are associated with suicide among adults in the general population, but with clear differences in their relative strength. PROSPERO REGISTRATION NUMBER: CRD42021232878.

Indexed as

Mental DisordersSelf-Injurious BehaviorSuicide PreventionAdultAutopsyHumansRisk FactorsAdult psychiatrySuicide & self-harm

Identifiers

PMID36162975
PMCPMC9685708

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.