Evidence map›Paper›PMID 36161928›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2022

Single-molecule investigations of single-chain cellulose biosynthesis.

Mark A Hilton, Harris W Manning, Ireneusz Górniak, Sonia K Brady, Madeline M Johnson, Jochen Zimmer, Matthew J Lang

Open access · hybridAbstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.9field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 12 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Biphasic mechanochemistry of single-chain polymerization.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Mark A HiltonDepartment of Chemical and Biomolecular Engineering, Vanderbilt University, Nashville, TN 37235.
Harris W ManningDepartment of Chemical and Biomolecular Engineering, Vanderbilt University, Nashville, TN 37235.
Ireneusz GórniakDepartment of Molecular Physiology and Biological Physics, University of Virginia, Charlottesville, VA 22908.ORCID 0000-0003-0357-6980
Sonia K BradyDepartment of Chemical and Biomolecular Engineering, Vanderbilt University, Nashville, TN 37235.
Madeline M JohnsonDepartment of Chemical and Biomolecular Engineering, Vanderbilt University, Nashville, TN 37235.
Jochen ZimmerDepartment of Molecular Physiology and Biological Physics, University of Virginia, Charlottesville, VA 22908.
Matthew J LangDepartment of Chemical and Biomolecular Engineering, Vanderbilt University, Nashville, TN 37235.ORCID 0000-0002-8198-144X
Vanderbilt University · USUniversity of Virginia · US

Funding

MOLECULAR BIOPHYSICS TRAINING PROGRAM AT VANDERBILTT32GM008320 · NIGMS · VANDERBILT UNIVERSITY · PI CHAZIN, WALTER J. · 1989 to 2023
$7.9M
Mechanism of Cellulose Synthesis and Transport Across Biological MembranesR01GM101001 · NIGMS · UNIVERSITY OF VIRGINIA · PI ZIMMER, JOCHEN · 2012 to 2021
$3.7M
HHS | National Institutes of Health (NIH) 5R01GM101001Howard Hughes Medical InstituteNIGMS NIH HHS R01 GM101001NIGMS NIH HHS T32 GM008320
6 · The paper itself

Abstract

Cellulose biosynthesis in sessile bacterial colonies originates in the membrane-integrated bacterial cellulose synthase (Bcs) AB complex. We utilize optical tweezers to measure single-strand cellulose biosynthesis by BcsAB from

Indexed as

Rhodobacter sphaeroidesUridine Diphosphate GlucoseCarbohydrate MetabolismCelluloseGlucoseCelluloseGlucoseUridine Diphosphate Glucosebiosynthesiscellulosecellulose synthaseoptical tweezerssingle-molecule studies

Identifiers

PMID36161928
PMCPMC9546554
OpenAlexW4297092964

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.