ArticleProceedings of the National Academy of Sciences of the United States of America2022
Hippocampal ripples signal contextually mediated episodic recall.
Article in Proceedings of the National Academy of Sciences of the United States of America, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.
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Who cites it
27 citing papers in PubMed.
- Hippocampal ripples initiate cortical dimensionality expansion for memory retrieval.Nature communications · 2026Article
- Review
- Human hippocampal ripples coordinate planning sequences and compositional representations in neocortex.Nature neuroscience · 2026Article
- Arousal state modulates human hippocampal ripples.bioRxiv : the preprint server for biology · 2026Article
- Differential Coding of Associative Memory Information in the Macaque Lateral Prefrontal Cortex and Hippocampus.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2026Article
- Global coincident bursts of high frequency oscillations across the human cortex coordinate large-scale memory processing.Nature communications · 2026Article
- Sensory encoding and memory retrieval are coordinated with propagating waves in the human brain.Nature communications · 2026Article
- Aperiodic 1/f noise drives ripple activity in humans.Nature communications · 2026Article
- Exercise enhances hippocampal-cortical ripple interactions in the human brain.Brain communications · 2026Article
- Spatiotemporal patterns differentiate hippocampal sharp-wave ripples from interictal epileptiform discharges in mice and humans.Nature communications · 2025Article
- Ripple contributions to human memory: making the spiking content count.Nature reviews. Neuroscience · 2025Review
- Motifs of human high-frequency oscillations structure processing and memory of continuous audiovisual narratives.Science advances · 2025Article
- Movie-watching evokes ripple-like activity within events and at event boundaries.Nature communications · 2025Article
- Sustained Hippocampal Theta Oscillations Reflect Experience-Dependent Learning in Backward Temporal Order Memory Retrieval.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2025Article
- Hippocampal and cortical high-frequency oscillations orchestrate human semantic networks during word list memory.iScience · 2025Article
- Dentate gyrus ensembles gate context-dependent neural states and memory retrieval.Science advances · 2024Article
- Ripple-locked coactivity of stimulus-specific neurons and human associative memory.Nature neuroscience · 2024Article
- Human Hippocampal Ripples Signal Encoding of Episodic Memories.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2024Article
- Awake ripples enhance emotional memory encoding in the human brain.Nature communications · 2024Article
- White matter network underlying semantic processing: evidence from stroke patients.Brain communications · 2024Article
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2 authors.
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Abstract
High-frequency oscillatory events, termed ripples, represent synchrony of neural activity in the brain. Recent evidence suggests that medial temporal lobe (MTL) ripples support memory retrieval. However, it is unclear if ripples signal the reinstatement of episodic memories. Analyzing electrophysiological MTL recordings from 245 neurosurgical participants performing episodic recall tasks, we find that the rate of hippocampal ripples rises just prior to the free recall of recently formed memories. This prerecall ripple effect (PRE) is stronger in the CA1 and CA3/dentate gyrus (CA3/DG) subfields of the hippocampus than the neighboring MTL regions entorhinal and parahippocampal cortex. PRE is also stronger prior to the retrieval of temporally and semantically clustered, as compared with unclustered, recalls, indicating the involvement of ripples in contextual reinstatement, which is a hallmark of episodic memory.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.