Evidence map›Paper›PMID 36161860›Full record

ArticleBMJ open ophthalmology2022

Association between personality traits and experience of adverse periocular reactions to topical prostaglandin analogues.

Nanami Kishimoto, Takahiko Noro, Fumitoshi Kodaka, Mei Kurosawa, Yoshinori Itoh, Shumpei Ogawa, Tomoyuki Watanabe, Masaomi Kubota, Kiyotaka Hori, Masahiro Shigeta and 1 more

Open access · goldAbstract read
In one paragraph

Article in BMJ open ophthalmology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 88% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 1 country.

Nanami Kishimoto *Department of Ophthalmology, The Jikei University School of Medicine, Minato-ku, Tokyo, Japan.
Takahiko Noro *Department of Ophthalmology, The Jikei University School of Medicine, Minato-ku, Tokyo, Japan t-noro@jikei.ac.jp.ORCID 0000-0001-9147-5455
Fumitoshi Kodaka *Department of Psychiatry, The Jikei University School of Medicine, Minato-ku, Tokyo, Japan.ORCID 0000-0002-9296-5736
Mei KurosawaDepartment of Ophthalmology, The Jikei University School of Medicine, Minato-ku, Tokyo, Japan.
Yoshinori ItohDepartment of Ophthalmology, The Jikei University School of Medicine, Minato-ku, Tokyo, Japan.
Shumpei OgawaDepartment of Ophthalmology, The Jikei University School of Medicine, Minato-ku, Tokyo, Japan.ORCID 0000-0003-3841-6004
Tomoyuki WatanabeDepartment of Ophthalmology, The Jikei University School of Medicine, Minato-ku, Tokyo, Japan.
Masaomi KubotaDepartment of Ophthalmology, The Jikei University School of Medicine, Minato-ku, Tokyo, Japan.ORCID 0000-0002-2314-8767
Kiyotaka HoriJapan Medical Affairs, Santen Pharmaceutical Co Ltd, Osaka, Japan.
Masahiro ShigetaDepartment of Psychiatry, The Jikei University School of Medicine, Minato-ku, Tokyo, Japan.
Tadashi NakanoDepartment of Ophthalmology, The Jikei University School of Medicine, Minato-ku, Tokyo, Japan.
Jikei University School of Medicine · JPSanten (Japan) · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAesthetically unappealing adverse periocular reactions to prostaglandin (PG) eye-drops are a major challenge in glaucoma treatment. This study analysed the personality traits of patients with glaucoma based on a five-factor model and examined the associations between these factors and adverse periocular reactions.

methodsOne hundred and forty-seven patients with glaucoma were surveyed anonymously regarding their personality traits and how often adverse periocular reactions were experienced.

resultsThe analysis included 117 valid responses (71 men and 46 women, age: 61.9±11.5 years). Patients who experienced hypertrichosis of the eyelashes scored significantly higher on extraversion (p<0.05), with no significant differences in the other four personality traits. Patients who experienced eyelid hyperpigmentation and deepening of the upper eyelid sulcus showed no significant differences in any of the personality traits. Younger patients scored significantly higher on hypertrichosis (p<0.05).

conclusionThe experience of adverse reactions differed according to patient age and personality traits. Therefore, eye-drops should be chosen based on these factors. TRIAL REGISTRATION NUMBER: UMIN000035155.

Indexed as

EyelashesGlaucomaHypertrichosisAgedFemaleHumansMaleMiddle AgedOphthalmic SolutionsPersonalityProstaglandins, SyntheticOphthalmic SolutionsProstaglandins, Syntheticeye lidsglaucomatreatment other

Identifiers

PMID36161860
PMCPMC9234788
OpenAlexW4283377669

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.