Evidence map›Paper›PMID 36161704›Full record

ArticleJournal of diabetes investigation2023

Sex differences in the association between visceral adipose tissue and atherosclerosis in type 2 diabetes patients with normal bodyweight: A study in a Chinese population.

Kun Xu, Qidong Zheng, Jianlin Shao, Lin Yang, Yuancheng Dai, Jingyuan Zhang, Yao Liang, Wenhao Huang, Yajun Liu, Jian Cheng and 4 more

Open access · goldAbstract read
In one paragraph

Article in Journal of diabetes investigation, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
1.8field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 14 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 6 institutions in 1 country.

Kun Xu *Department of Internal Medicine, Shengzhou Hospital of Traditional Chinese Medicine, Shengzhou, China.ORCID https://orcid.org/0000-0003-1813-2880
Qidong Zheng *Department of Internal Medicine, The Second People's Hospital of Yuhuan, Taizhou, China.
Jianlin Shao *Zhejiang Provincial Center for Cardiovascular Disease Prevention and Control, Zhejiang Hospital, Hangzhou, China.
Lin YangDepartment of Geriatrics, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China.
Yuancheng DaiDepartment of Internal Medicine of Traditional Chinese Medicine, Sheyang Diabetes Specialist Hospital, Yancheng, China.
Jingyuan ZhangDepartment of Medicine, The Second College of Clinical Medicine, Zhejiang Chinese Medical University, Hangzhou, China.
Yao LiangDepartment of Internal Medicine, The Second People's Hospital of Yuhuan, Taizhou, China.
Wenhao HuangDepartment of Medicine, The Second College of Clinical Medicine, Zhejiang Chinese Medical University, Hangzhou, China.
Yajun LiuDepartment of Medicine, The Second College of Clinical Medicine, Zhejiang Chinese Medical University, Hangzhou, China.
Jian ChengDepartment of Internal Medicine, The Second People's Hospital of Yuhuan, Taizhou, China.
Yuping PanDepartment of Internal Medicine, The Second People's Hospital of Yuhuan, Taizhou, China.
Mengyao YangDepartment of Internal Medicine, The Second People's Hospital of Yuhuan, Taizhou, China.
Lijiang TangDepartment of Cardiology, Zhejiang Hospital, Hangzhou, China.
Changqing DuDepartment of Cardiology, Zhejiang Hospital, Hangzhou, China.ORCID https://orcid.org/0000-0003-4992-7977
Taizhou Second People's Hospital · CNZhejiang Chinese Medical University · CNZhejiang Hospital · CNAnyang Hospital of Traditional Chinese Medicine · CNFirst Affiliated Hospital Zhejiang University · CNHangzhou Hospital of Traditional Chinese Medicine · CN

Funding

the grant from Science and technology Bureau of Zhejiang Province LGF20H02006the health science and technology plan of Taizhou science and technology bureau 20180709the Major medical and health science and technology plan of Zhejiang Province WKJ-ZJ-1913the Natural Science Foundation of Zhejiang Province LY21H020002
6 · The paper itself

Abstract

AIMS/

introductionTo investigate the impact of visceral adipose tissue (VAT) on atherosclerosis in type 2 diabetes patients with normal bodyweight (OB[-]) in the Chinese population, and to further assess the sex-age differences between them. MATERIALS AND

methodsA total of 8,839 type 2 diabetes patients from two of the National Metabolic Management Centers in China were included in this study. Participants were classified into four groups by visceral fat area (VFA; cm

resultsThe VA(+)OB(-) prevalence was 3.7% among these participants. Patients with VA(+)OB(-) had the highest baPWV value (P < 0.001) and the highest proportion of the tertile 3 of baPWV (P < 0.001) among four groups, and were significantly associated with baPWV (standardized β = 0.026, P = 0.008). VFA was significantly related to tertile 2 to tertile 3 of baPWV in (OB[-]) type 2 diabetes patients, when compared with tertile 1 of baPWV, respectively. In sex-age stratified analysis, the association of VFA and the tertiles of baPWV showed sex differences. For the 55 years age stratification analysis, there was no age difference in the relationship between VFA and baPWV in (OB[-]) patients.

conclusionIncreased VAT was an independent risk factor for atherosclerosis in female type 2 diabetes patients with normal weight.

Indexed as

AtherosclerosisDiabetes Mellitus, Type 2Vascular StiffnessAnkle Brachial IndexBody WeightEast Asian PeopleFemaleHumansIntra-Abdominal FatMalePulse Wave AnalysisRisk FactorsSex CharacteristicsAtherosclerosisType 2 diabetesVisceral adipose tissue

Identifiers

PMID36161704
PMCPMC9807154
OpenAlexW4297221983

What OpenQuestion holds

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LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.