Evidence map›Paper›PMID 36161672›Full record

ArticleMagnetic resonance in medicine2023

Mitigating the impact of flip angle and orientation dependence in single compartment R2* estimates via 2-pool modeling.

Giorgia Milotta, Nadège Corbin, Christian Lambert, Antoine Lutti, Siawoosh Mohammadi, Martina F Callaghan

Open access · hybridAbstract read
In one paragraph

Article in Magnetic resonance in medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.7field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
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  5. Fiber-orientation independent component of RFrontiers in neuroscience · 2023
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 4 countries.

Giorgia MilottaWellcome Centre for Human Neuroimaging, UCL Queen Square Institute of Neurology, University College London, London, United Kingdom.ORCID 0000-0002-3403-3754
Nadège CorbinWellcome Centre for Human Neuroimaging, UCL Queen Square Institute of Neurology, University College London, London, United Kingdom.
Christian LambertWellcome Centre for Human Neuroimaging, UCL Queen Square Institute of Neurology, University College London, London, United Kingdom.
Antoine LuttiLaboratory for Research in Neuroimaging, Department for Clinical Neuroscience, Lausanne University Hospital and University of Lausanne, Lausanne, Switzerland.
Siawoosh MohammadiDepartment of Systems Neurosciences, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
Martina F CallaghanWellcome Centre for Human Neuroimaging, UCL Queen Square Institute of Neurology, University College London, London, United Kingdom.ORCID 0000-0003-0374-1659
Wellcome Centre for Human Neuroimaging · GBCentre National de la Recherche Scientifique · FRUniversität Hamburg · DEUniversity of Lausanne · CH

Funding

Medical Research Council MR/X023494/1Wellcome TrustWellcome Trust 203147/Z/16/Z
6 · The paper itself

Abstract

purposeThe effective transverse relaxation rate (

methodsWe used 2-pool (myelin and non-myelin water) simulations to characterize the bias in single compartment

results

conclusionWe have demonstrated and validated a simple approach that mitigates flip angle and orientation biases in single-compartment

Indexed as

Magnetic Resonance ImagingMyelin SheathBrainReproducibility of ResultsWaterWatermono-exponentialmulti-compartmentR2* mappingsingle compartmentT2*VFA

Identifiers

PMID36161672
PMCPMC9827921
OpenAlexW4297229562

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.