Evidence map›Paper›PMID 36161381›Full record

ArticleJournal of veterinary internal medicine2022

A 50-step walking test for analysis of recovery after decompressive surgery for thoracolumbar disc herniation in dogs.

Suzanne Rosen, Jessica Lynn Grzegorzewski, Stephanie Heath, Cynthia Schocke, Nicholas Jeffery

Open access · goldAbstract read
In one paragraph

Article in Journal of veterinary internal medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.1field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 5 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Suzanne RosenSmall Animal Clinical Sciences, Texas A&M University, College Station, Texas, USA.
Jessica Lynn GrzegorzewskiSmall Animal Clinical Sciences, Texas A&M University, College Station, Texas, USA.
Stephanie HeathSmall Animal Clinical Sciences, Texas A&M University, College Station, Texas, USA.
Cynthia SchockeSmall Animal Clinical Sciences, Texas A&M University, College Station, Texas, USA.
Nicholas JefferySmall Animal Clinical Sciences, Texas A&M University, College Station, Texas, USA.ORCID https://orcid.org/0000-0002-9812-1788
Texas College · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundDespite its importance, there is no agreed definition of recovery of ambulation in dogs with spinal cord injury.

objectivesTo validate a new walking test in dogs recovering from thoracolumbar spinal cord injury. ANIMALS: Two hundred twenty-four dogs weighing <20 kg: 120 normally ambulatory dogs, plus 104 dogs undergoing decompressive surgery for acute thoracolumbar intervertebral disc herniation.

methodsProspective cohort studies. The distance each freely-ambulatory dog walked during 50 step cycles was regressed on ulna length. For each postsurgical dog, we recorded when the calculated 50-step distance was completed without falling, or their inability to complete this distance by 4 months or more after surgery. Bayesian analysis compared outcomes for presurgical neurologic categories; association of recovery with several preoperative variables was explored using logistic and time-to-event regression.

resultsFor control dogs, 50-step distance (m) = 1.384 × ulnar length (cm) + 2.773. In postsurgical dogs, the 50-step test provided decisive evidence that deep pain-negative dogs were less likely to recover ambulation than dogs with intact pain perception (12/29 recovered vs 71/75; Bayes factor [BF] = 5.9 × 10 CONCLUSIONS AND CLINICAL IMPORTANCE: This straightforward 50-step walking test provides robust data on ambulatory recovery well-suited to large scale pragmatic trials on treatment of thoracolumbar spinal cord injury in dogs.

Indexed as

Dog DiseasesIntervertebral Disc DisplacementSpinal Cord InjuriesAnimalsBayes TheoremDogsExercise TestHumansProspective StudiesRetrospective StudiesWalkingambulationlocomotionoutcome measurespinal cord injury

Identifiers

PMID36161381
PMCPMC9511074
OpenAlexW4292488006

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.