ArticleExploratory research in clinical and social pharmacy2022
Factors associated with medication non-adherence among patients with severe mental disorder - A cross sectional study in a tertiary care centre.
Article in Exploratory research in clinical and social pharmacy, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 3 of them syntheses that pooled it.
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Who cites it
18 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- Examining the relationship between healthcare practitioners' communication and patient adherence to treatment: a systematic review.BMC health services research · 2026Pooled it
- Non-adherence level of pharmacotherapy and its predictors among mental disorders in a resource-limited life trajectories: a systematic review and meta-analysis.BMC psychiatry · 2025Pooled it
- Clozapine and Pneumonia: Synthesizing the Link by Reviewing Existing Reports-A Systematic Review and Meta-Analysis.Medicina (Kaunas, Lithuania) · 2024Pooled it
- Observational
- Factors associated with non-adherence to clinic visits among patients with severe mental illness enrolled in the SMILE study in Uganda.BMC psychiatry · 2025Article
- Expanding our understanding of (mal)adapted stress physiology in psychiatric disorders: achieving single-cell characterisation of steroids and neuropeptides.Neurobiology of stress · 2025Review
- Evaluating the efficacy of blister packaging in improving medication adherence within psychiatry: A systematic literature review.The mental health clinician · 2025Review
- Attitudes of Australian patients receiving inpatient mental health care towards deprescribing: a cross-sectional survey.BMC psychiatry · 2025Article
- Article
- Obesity and Atherosclerotic Cardiovascular Disease: A Review of Social and Biobehavioral Pathways.Methodist DeBakey cardiovascular journal · 2025Review
- Assessments of the Factor Structure and Psychometric Properties of the Persian Version of the 30-Item Drug Attitude Inventory in Patients with Schizophrenia.Addiction & health · 2025Article
- Types of Medication Non-adherence & Approaches to Enhance Medication Adherence in Mental Health Disorders: A Narrative Review.Indian journal of psychological medicine · 2024Review
- Medication non-adherence and associated factors among peoples with schizophrenia: multicenter cross-sectional study in Northwest Ethiopia.BMC psychiatry · 2024Article
- Detrimental Impact of Comorbid Mental Disorders in Chronic Thromboembolic Pulmonary Hypertension - A Retrospective Observational Study.Circulation reports · 2024Article
- Lived experiences of adults' non-compliance with psychiatric medication for depression.The South African journal of psychiatry : SAJP : the journal of the Society of Psychiatrists of South Africa · 2024Article
- Article
- Therapeutic Adherence of People with Mental Disorders: An Evolutionary Concept Analysis.International journal of environmental research and public health · 2023Review
- Physical activity influences adherence to pharmacological treatments in patients with severe mental disorders: results from the multicentric, randomized controlled LIFESTYLE trial.Frontiers in pharmacology · 2023Article
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Medications are an essential treatment modality of mental disorders. There is limited scientific literature on medication non-adherence among patients in Severe Mental Disorders with respect to patient-related factors. The current study explores the factors associated with medication non-adherence in such patients. Objectives: To study the relationship between socio-demographic, clinical, treatment related factors, self-stigma, patients' & caregivers' attitude towards psychotropic medications, doctor-patient communication and medication non-adherence in patients with severe mental disorders. Methods: A cross-sectional observation study, where patients with severe mental disorders attending Psychiatry Outpatient services, and their caregivers, were recruited. Sociodemographic and clinical variables were recorded using data collection form and illness-specific severity scales. Patients were administered Medication adherence rating scale (MARS), Internalised stigma of mental illness inventory (ISMI- 9), Attitude of patients towards psychotropic medication scale and Doctor-patient communication questionnaire (DPCQ). The Attitude of caregivers towards psychotropic medication scale was administered for caregivers. Results: Among 152 patients, 58 (38.16%) patients had a diagnosis of schizophrenia, 11 (7.24%) had delusional disorder, 32 (21.05%) patients were diagnosed with bipolar disorder type 1 - mania and 19 (12.50) with bipolar disorder type 2 - depression whereas 32 (21.05%) had major depressive disorder. Majority of the patients were non-adherent to medications (88.16%). MARS score was significantly higher among patients of middle socioeconomic class ( Conclusion: Medication adherence was higher among patients belonging to uppermiddle socioeconomic status, urban domicile and higher caregiver age. Higher severity of illness, self-stigma and negative attitude of patients and caregivers towards psychotropic medications were associated with lower adherence whereas better doctor-patient communication was associated with higher adherence to medications.
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