Evidence map›Paper›PMID 36161180›Full record

ArticleFrontiers in neuroscience2022

Image registration and appearance adaptation in non-correspondent image regions for new MS lesions detection.

Julia Andresen, Hristina Uzunova, Jan Ehrhardt, Timo Kepp, Heinz Handels

Abstract read
In one paragraph

Article in Frontiers in neuroscience, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Julia AndresenInstitute of Medical Informatics, University of Lübeck, Lübeck, Germany.
Hristina UzunovaGerman Research Center for Artificial Intelligence, Lübeck, Germany.
Jan EhrhardtInstitute of Medical Informatics, University of Lübeck, Lübeck, Germany.
Timo KeppInstitute of Medical Informatics, University of Lübeck, Lübeck, Germany.
Heinz HandelsInstitute of Medical Informatics, University of Lübeck, Lübeck, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Manual detection of newly formed lesions in multiple sclerosis is an important but tedious and difficult task. Several approaches for automating the detection of new lesions have recently been proposed, but they tend to either overestimate the actual amount of new lesions or to miss many lesions. In this paper, an image registration convolutional neural network (CNN) that adapts the baseline image to the follow-up image by spatial deformations and simulation of new lesions is proposed. Simultaneously, segmentations of new lesions are generated, which are shown to reliably estimate the real new lesion load and to separate stable and progressive patients. Several applications of the proposed network emerge: image registration, detection and segmentation of new lesions, and modeling of new MS lesions. The modeled lesions offer the possibility to investigate the intensity profile of new lesions.

Indexed as

convolutional neural networksimage registrationmultiple sclerosisnew lesionsnon-correspondencesshape and appearance adaptation

Identifiers

PMID36161180
PMCPMC9490269

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.