Evidence map›Paper›PMID 36161130›Full record

ArticlePreventive medicine reports2022

Barriers to human papillomavirus (HPV) vaccination among young adults, aged 18-35.

Meera Muthukrishnan, Travis Loux, Enbal Shacham, Jasmin A Tiro, Lauren D Arnold

Abstract read
In one paragraph

Article in Preventive medicine reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Motivated by mortality:Exploratory research in clinical and social pharmacy · 2026
    Article
  3. Knowledge, Attitudes, and Behaviors Regarding HPV Vaccination and Self-Sampling Among US Young Adults.Journal of cancer education : the official journal of the American Association for Cancer Education · 2026
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  9. Barriers in the prevention and early detection of human papillomavirus in Latin America.International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Meera MuthukrishnanUniversity of Texas Southwestern Medical Center, Department of Population and Data Sciences, USA.
Travis LouxSaint Louis University, College for Public Health and Social Justice, Department of Epidemiology and Biostatistics, USA.
Enbal ShachamSaint Louis University, College for Public Health and Social Justice, Department of Behavioral Science and Health Education, USA.
Jasmin A TiroUniversity of Texas Southwestern Medical Center, Department of Population and Data Sciences, USA.
Lauren D ArnoldSaint Louis University, College for Public Health and Social Justice, Department of Epidemiology and Biostatistics, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In the United States (US), an estimated 35,900 human papillomavirus (HPV)-related cancers are diagnosed annually. HPV vaccines are projected to eliminate ∼90% of these cancers. Routine vaccination is recommended at age 11-12 with "catch-up" vaccination through age 26 and shared clinical decision making for ages 27-45. However, vaccine uptake has been slow with many young adults remaining unvaccinated. This study examined barriers to HPV vaccination among individuals aged 18-35 years and assessed likelihood of future HPV vaccination. Age-eligible participants (n = 499) recruited through Facebook advertisements, Facebook posts, and clinics (6/2019-3/2020) completed an online survey. Descriptive statistics and bivariate analysis examined HPV vaccine barriers and intent. Logistic regression models examined predictors of HPV vaccine intent. Most (57.1%) reported they were not at all likely to get vaccinated for HPV in the future. Lower intent was associated with belief that the vaccine is not necessary (aOR: 0.134, 95% CI: 0.073, 0.246) and not safe (aOR: 0.312, 95% CI: 0.126, 0.773). Intent was positively associated with the belief that health insurance would not cover vaccination (aOR: 2.226, 95% CI: 1.070, 4.631). Provider recommendation was not significantly associated with vaccine intention. This study highlights challenges to HPV vaccine uptake for young adults. Though several successful interventions exist, most target adolescents and their parents or providers. Future steps should use this evidence to inform development of targeted interventions to increase HPV vaccine intention and uptake in adults, ultimately reducing the burden of HPV-related cancers.

Indexed as

BarriersHPV vaccineHuman papillomavirusVaccine intentionsYoung adults

Identifiers

PMID36161130
PMCPMC9502683

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.