ArticleFrontiers in plant science2022
Tissue-specific transcriptomic analysis uncovers potential roles of natural antisense transcripts in
Article in Frontiers in plant science, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
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Who cites it
5 citing papers in PubMed.
- Regulatory Landscapes of Non-Coding RNAs During Drought Stress in Plants.International journal of molecular sciences · 2025Review
- Exploring the Regulatory Dynamics ofInternational journal of molecular sciences · 2024Article
- The plant siRNA landscape.The Plant cell · 2024Review
- Global identification of natural antisense transcripts iniScience · 2023Article
- Roles of long non-coding RNAs in plant immunity.PLoS pathogens · 2023Review
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Authors and funding
5 authors.
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Abstract
Natural antisense transcripts (NATs) are an important class of non-coding ribonucleic acids (RNAs) that have been shown to regulate gene expression. Using strand-specific RNA sequencing, 36,317 NAT pairs were identified, and 5,536 were specifically expressed under heat stress. We found distinct expression patterns between vegetative and reproductive tissues for both coding genes and genes encoding NATs. Genes for heat-responsive NATs are associated with relatively high levels of H3K4me3 and low levels of H3K27me2/3. On the other hand, small RNAs are significantly enriched in sequence overlapping regions of NAT pairs, and a large number of heat-responsive NATs pairs serve as potential precursors of nat-siRNAs. Collectively, our results suggest epigenetic modifications and small RNAs play important roles in the regulation of NAT expression, and highlight the potential significance of heat-inducible NATs.
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