Evidence map›Paper›PMID 36160931›Full record

ArticleToxicon: X2022

Mapping of clinical management resources for snakebites and other animal envenomings in the Brazilian Amazon.

Timothy P Beck, Anna Tupetz, Altair Seabra Farias, Alexandre Silva-Neto, Thiago Rocha, Emily R Smith, Felipe Murta, Flavio Santos Dourado, Deugles Cardoso, Tatyana A Ramos and 11 more

Abstract read
In one paragraph

Article in Toxicon: X, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Snakebite Envenomations In The Brazilian Amazon: A Little Less Neglected.Revista da Sociedade Brasileira de Medicina Tropical · 2026
    Review
  5. Review
  6. Review
  7. Article
  8. Review
  9. SERPENT-Brasil: a technological tool for snakebite management.Revista panamericana de salud publica = Pan American journal of public health · 2025
    Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

21 authors.

Timothy P BeckDepartment of Emergency Medicine, Department of Surgery, Durham, NC, 27710, USA.
Anna TupetzDepartment of Emergency Medicine, Department of Surgery, Durham, NC, 27710, USA.
Altair Seabra FariasSchool of Health Sciences, Universidade Do Estado Do Amazonas, Manaus, Brazil.
Alexandre Silva-NetoSchool of Health Sciences, Universidade Do Estado Do Amazonas, Manaus, Brazil.
Thiago RochaDepartment of Emergency Medicine, Department of Surgery, Durham, NC, 27710, USA.
Emily R SmithDepartment of Emergency Medicine, Department of Surgery, Durham, NC, 27710, USA.
Felipe MurtaSchool of Health Sciences, Universidade Do Estado Do Amazonas, Manaus, Brazil.
Flavio Santos DouradoTechnical Group of Venomous Animal, Ministério da Saúde, Brasília, Brazil.
Deugles CardosoZoonosis Department, Fundação de Vigilância Em Saúde Dra. Rosemary Costa Pinto, Manaus, Brazil.
Tatyana A RamosZoonosis Department, Fundação de Vigilância Em Saúde Dra. Rosemary Costa Pinto, Manaus, Brazil.
André SachettSchool of Health Sciences, Universidade Do Estado Do Amazonas, Manaus, Brazil.
Thiago Serrão PintoSchool of Pharmaceutical Sciences, Universidade Federal Do Amazonas, Manaus, Brazil.
Manuela Berto PuccaMedical School, Federal University of Roraima, Boa Vista, Roraima, Brazil.
Vanderson SampaioSchool of Health Sciences, Universidade Do Estado Do Amazonas, Manaus, Brazil.
Flavia RamosSchool of Health Sciences, Universidade Do Estado Do Amazonas, Manaus, Brazil.
João Nickenig VissociDepartment of Emergency Medicine, Department of Surgery, Durham, NC, 27710, USA.
Jacqueline SachettSchool of Health Sciences, Universidade Do Estado Do Amazonas, Manaus, Brazil.
Fan Hui WenButantan Institute, São Paulo, São Paulo, Brazil.
Catherine A StatonDepartment of Emergency Medicine, Department of Surgery, Durham, NC, 27710, USA.
Charles J GerardoDepartment of Emergency Medicine, Department of Surgery, Durham, NC, 27710, USA.
Wuelton MonteiroSchool of Health Sciences, Universidade Do Estado Do Amazonas, Manaus, Brazil.

Funding

Using community health centers to mitigate the impact of snakebite envenoming in low resource areasR21TW011944 · FIC · DUKE UNIVERSITY · PI GERARDO, CHARLES JOHN · 2021 to 2022
$534k
FIC NIH HHS R21 TW011944
6 · The paper itself

Abstract

Snakebite envenomings (SBEs) and other envenomings triggered by venomous animals (VAEs) represent a significant disease burden in Brazil, with 29,152 SBEs reported in 2021 alone with nearly half of those occurring in the remote Brazilian Amazon. In 2021, Brazil recorded 240,294 envenomings from snakes, scorpions, spiders, and caterpillars. Therefore, there is an unequal distribution of SBEs with high morbidity and mortality in the Brazilian Amazon. The severity of SBEs increases when patients require more than 6 h to access antivenom treatment, a common issue for the rural and indigenous populations. Understanding currently available resources and practices in Amazon remote areas of Brazil can serve to inform future interventions and guide health care policies. This study aims to develop a resource map of existing healthcare resources for the Brazilian Amazon's clinical management of VAEs with emphasis in SBEs, which will aid future strategic interventions. Data collection included a literature review, secondary data collected by government departments and organizational records, GIS mapping activities, and expert input. Our framework was guided by the three levels of healthcare service ecosystem analysis (macro, meso, and micro). Our resource map lays out a comprehensive overview of antivenom access, the distribution landscape, differences in patient transportation, and barriers to access healthcare that face populations in the Brazilian Amazon.

Indexed as

Access to careAV, AntivenomCommunity healthMoH, Brazilian Ministry of HealthNeglected tropical diseasesResource mapSBE, Snakebite envenomingSnakebite envenomingVAE, Venomous animals’ envenoming

Identifiers

PMID36160931
PMCPMC9489497

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.