Evidence map›Paper›PMID 36160840›Full record

ArticleFrontiers in physiology2022

Remote ischemic preconditioning enhances aerobic performance by accelerating regional oxygenation and improving cardiac function during acute hypobaric hypoxia exposure.

Zhifeng Zhong, Huaping Dong, Yu Wu, Simin Zhou, Hong Li, Pei Huang, Huaijun Tian, Xiaoxu Li, Heng Xiao, Tian Yang and 10 more

Abstract read
In one paragraph

Article in Frontiers in physiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Trial
  2. Article
  3. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

20 authors.

Zhifeng ZhongDepartment of High Altitude Operational Medicine, College of High Altitude Military Medicine, Army Medical University (Third Military Medical University), Chongqing, China.
Huaping DongDepartment of High Altitude Operational Medicine, College of High Altitude Military Medicine, Army Medical University (Third Military Medical University), Chongqing, China.
Yu WuDepartment of High Altitude Operational Medicine, College of High Altitude Military Medicine, Army Medical University (Third Military Medical University), Chongqing, China.
Simin ZhouDepartment of High Altitude Operational Medicine, College of High Altitude Military Medicine, Army Medical University (Third Military Medical University), Chongqing, China.
Hong LiDepartment of Anesthesiology, Xinqiao Hospital, Army Medical University (Third Military Medical University), Chongqing, China.
Pei HuangDepartment of High Altitude Operational Medicine, College of High Altitude Military Medicine, Army Medical University (Third Military Medical University), Chongqing, China.
Huaijun TianDepartment of High Altitude Operational Medicine, College of High Altitude Military Medicine, Army Medical University (Third Military Medical University), Chongqing, China.
Xiaoxu LiKey Laboratory of High Altitude Medicine, PLA, Army Medical University (Third Military Medical University), Chongqing, China.
Heng XiaoDepartment of High Altitude Operational Medicine, College of High Altitude Military Medicine, Army Medical University (Third Military Medical University), Chongqing, China.
Tian YangKey Laboratory of High Altitude Medicine, PLA, Army Medical University (Third Military Medical University), Chongqing, China.
Kun XiongKey Laboratory of High Altitude Medicine, PLA, Army Medical University (Third Military Medical University), Chongqing, China.
Gang ZhangKey Laboratory of High Altitude Medicine, PLA, Army Medical University (Third Military Medical University), Chongqing, China.
Zhongwei TangKey Laboratory of High Altitude Medicine, PLA, Army Medical University (Third Military Medical University), Chongqing, China.
Yaling LiDepartment of High Altitude Operational Medicine, College of High Altitude Military Medicine, Army Medical University (Third Military Medical University), Chongqing, China.
Xueying FanDepartment of High Altitude Operational Medicine, College of High Altitude Military Medicine, Army Medical University (Third Military Medical University), Chongqing, China.
Chao YuanKey Laboratory of High Altitude Medicine, PLA, Army Medical University (Third Military Medical University), Chongqing, China.
Jiaolin NingDepartment of Anesthesiology, First Affiliated Hospital, Army Medical University (Third Military Medical University), Chongqing, China.
Yue LiDepartment of Anesthesiology, First Affiliated Hospital, Army Medical University (Third Military Medical University), Chongqing, China.
Jiaxin XieDepartment of High Altitude Operational Medicine, College of High Altitude Military Medicine, Army Medical University (Third Military Medical University), Chongqing, China.
Peng LiDepartment of High Altitude Operational Medicine, College of High Altitude Military Medicine, Army Medical University (Third Military Medical University), Chongqing, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Remote ischemic preconditioning (RIPC) may improve exercise performance. However, the influence of RIPC on aerobic performance and underlying physiological mechanisms during hypobaric hypoxia (HH) exposure remains relatively uncertain. Here, we systematically evaluated the potential performance benefits and underlying mechanisms of RIPC during HH exposure. Seventy-nine healthy participants were randomly assigned to receive sham intervention or RIPC (4 × 5 min occlusion 180 mm Hg/reperfusion 0 mm Hg, bilaterally on the upper arms) for 8 consecutive days in phases 1 (24 participants) and phase 2 (55 participants). In the phases 1, we measured the change in maximal oxygen uptake capacity (VO

Indexed as

cardiac functionheat shock proteinshypobaric hypoxiamaximal oxygen uptakeregional oxygenationremote ischemic preconditioningthymosin beta-4

Identifiers

PMID36160840
PMCPMC9500473

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.