Evidence map›Paper›PMID 36160805›Full record

ArticleFrontiers in pediatrics2022

A non-randomized comparative study of olfactory and gustatory functions in children who recovered from COVID-19 (1-year follow-up).

Leyla Namazova-Baranova, George Karkashadze, Irina Zelenkova, Elena Vishneva, Elena Kaytukova, Dina Rusinova, Natalia Ustinova, Natalia Sergienko, Yulia Nesterova, Leonid Yatsyk and 14 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in pediatrics, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

24 authors.

Leyla Namazova-BaranovaPediatrics and Child Health Research Institute, Russian Scientific Center of Surgery Named After Academician B. V. Petrovsky, Moscow, Russia.
George KarkashadzePediatrics and Child Health Research Institute, Russian Scientific Center of Surgery Named After Academician B. V. Petrovsky, Moscow, Russia.
Irina ZelenkovaPediatrics and Child Health Research Institute, Russian Scientific Center of Surgery Named After Academician B. V. Petrovsky, Moscow, Russia.
Elena VishnevaPediatrics and Child Health Research Institute, Russian Scientific Center of Surgery Named After Academician B. V. Petrovsky, Moscow, Russia.
Elena KaytukovaPediatrics and Child Health Research Institute, Russian Scientific Center of Surgery Named After Academician B. V. Petrovsky, Moscow, Russia.
Dina RusinovaPirogov Russian National Research Medical University, Moscow, Russia.
Natalia UstinovaPediatrics and Child Health Research Institute, Russian Scientific Center of Surgery Named After Academician B. V. Petrovsky, Moscow, Russia.
Natalia SergienkoPediatrics and Child Health Research Institute, Russian Scientific Center of Surgery Named After Academician B. V. Petrovsky, Moscow, Russia.
Yulia NesterovaPediatrics and Child Health Research Institute, Russian Scientific Center of Surgery Named After Academician B. V. Petrovsky, Moscow, Russia.
Leonid YatsykPediatrics and Child Health Research Institute, Russian Scientific Center of Surgery Named After Academician B. V. Petrovsky, Moscow, Russia.
Dmitrii KratkoPediatrics and Child Health Research Institute, Russian Scientific Center of Surgery Named After Academician B. V. Petrovsky, Moscow, Russia.
Svetlana GubanovaPediatrics and Child Health Research Institute, Russian Scientific Center of Surgery Named After Academician B. V. Petrovsky, Moscow, Russia.
Viktor GankovskiyPediatrics and Child Health Research Institute, Russian Scientific Center of Surgery Named After Academician B. V. Petrovsky, Moscow, Russia.
Tina GogberashviliPediatrics and Child Health Research Institute, Russian Scientific Center of Surgery Named After Academician B. V. Petrovsky, Moscow, Russia.
Tatiana KonstantinidiPediatrics and Child Health Research Institute, Russian Scientific Center of Surgery Named After Academician B. V. Petrovsky, Moscow, Russia.
Darya BushuevaPediatrics and Child Health Research Institute, Russian Scientific Center of Surgery Named After Academician B. V. Petrovsky, Moscow, Russia.
Anastasia RykunovaDepartment of Health, City Child Polyclinics No 133, Moscow, Russia.
Elena ShirdaninaDepartment of Health, City Child Polyclinics No 133, Moscow, Russia.
Svetlana SadilloevaPediatrics and Child Health Research Institute, Russian Scientific Center of Surgery Named After Academician B. V. Petrovsky, Moscow, Russia.
Natalia SergeevaPediatrics and Child Health Research Institute, Russian Scientific Center of Surgery Named After Academician B. V. Petrovsky, Moscow, Russia.
Anastasia LamasovaPediatrics and Child Health Research Institute, Russian Scientific Center of Surgery Named After Academician B. V. Petrovsky, Moscow, Russia.
Elizaveta LeonovaPediatrics and Child Health Research Institute, Russian Scientific Center of Surgery Named After Academician B. V. Petrovsky, Moscow, Russia.
Alina PankovaPediatrics and Child Health Research Institute, Russian Scientific Center of Surgery Named After Academician B. V. Petrovsky, Moscow, Russia.
Ekaterina DubonosovaPediatrics and Child Health Research Institute, Russian Scientific Center of Surgery Named After Academician B. V. Petrovsky, Moscow, Russia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The experimental group included 68 children over 6 years of age who had recovered from COVID-19. The control group included 22 children over 6 years of age who have never had COVID-19. Research methods included neurological examination, verification of cognitive status, examination by an otolaryngologist, and smell and taste assessment. The examination was performed 6-8 weeks after COVID-19 recovery and after 1 year in some patients. Children who recovered from COVID-19 had a reduction in their ability to smell compared to children who had never had COVID-19. The olfactory thresholds and taste identification scores after recovery from COVID-19 were identical, whether the parents had reported anosmia in their children during COVID-19 or not, and irrespective of hyperthermia level and the presence or absence of headache and hyperhidrosis during COVID-19. Analysis of correlation with neuropsychiatric symptoms showed no differences in the olfactory thresholds in children irrespective of the presence of neuropsychiatric symptoms (tics, tremors, enuresis, compulsive movements, seizures, speech disorders, attention deficit, and easy fatigability) both in general, and in particular among subjects performing or not any compulsive movements, and experiencing or not a combination of easy fatigability and daytime sleepiness. Evidence suggests that in children and adolescents, partial hyposmia is associated with depressive symptoms, varying in severity from low to high, but symptoms of depression were not caused by COVID-19 infection itself. Analysis in subgroups with different degrees of state and trait anxiety did not reveal any significant differences in the olfactory threshold. A re-examination of 21 children was performed after 1 year. An objective olfactometric examination showed that the sensitivity to odorants increased significantly. In 1 year, we compared the thresholds of smell in children who had COVID-19 and those who did not have this disease: olfactory sensitivity after COVID-19 in children is restored to normal values. Schulte correction test showed that none of 14 children with asthenic manifestations in the form of fluctuations or exhaustion when performing the test immediately after COVID-19 had these manifestations after 1 year. Thus, asthenization of cognitive activity was recorded within the next 1.5 months after suffering from COVID-19 but was absent after 1 year.

Indexed as

childrencognitive functionsCOVID-19olfactometryolfactory and gustatory functions

Identifiers

PMID36160805
PMCPMC9505991

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.