Evidence map›Paper›PMID 36160745›Full record

ReviewWorld journal of gastrointestinal oncology2022

Poorly cohesive cells gastric carcinoma including signet-ring cell cancer: Updated review of definition, classification and therapeutic management.

Vincent Drubay, Frederiek Nuytens, Florence Renaud, Antoine Adenis, Clarisse Eveno, Guillaume Piessen

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in World journal of gastrointestinal oncology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed.

  1. Article
  2. The significance of small lymph nodes on CT for advanced poorly cohesive gastric carcinoma.Cancer imaging : the official publication of the International Cancer Imaging Society · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Vincent DrubayDepartment of Digestive and Oncological Surgery, University Lille, Claude Huriez University Hospital, Lille 59000, France.
Frederiek NuytensDepartment of Digestive and Oncological Surgery, University Lille, Claude Huriez University Hospital, Lille 59000, France.
Florence RenaudDepartment of Pathology, University Lille Hospital, Lille 59000, France.
Antoine AdenisFREGAT Network, Claude Huriez University Hospital, Lille 59000, France.
Clarisse EvenoDepartment of Digestive and Oncological Surgery, University Lille, Claude Huriez University Hospital, Lille 59000, France.
Guillaume PiessenDepartment of Digestive and Oncological Surgery, University Lille, Claude Huriez University Hospital, Lille 59000, France.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

While the incidence of gastric cancer (GC) in general has decreased worldwide in recent decades, the incidence of diffuse cancer historically comprising poorly cohesive cells-GC (PCC-GC) and including signet ring cell cancer is rising. Literature concerning PCC-GC is scarce and unclear, mostly due to a large variety of historically used definitions and classifications. Compared to other histological subtypes of GC, PCC-GC is nevertheless characterized by a distinct set of epidemiological, histological and clinical features which require a specific diagnostic and therapeutic approach. The aim of this review was to provide an update on the definition, classification and therapeutic strategies of PCC-GC. We focus on the updated histological definition of PCC-GC, along with its implications on future treatment strategies and study design. Also, specific considerations in the diagnostic management are discussed. Finally, the impact of some recent developments in the therapeutic management of GC in general such as the recently validated taxane-based regimens (5-Fluorouracil, leucovorin, oxaliplatin and docetaxel), the use of hyperthermic intraperitoneal chemotherapy as well as pressurized intraperitoneal aerosol chemotherapy and targeted therapy have been reviewed in depth for their relative importance for PCC-GC in particular.

Indexed as

ClassificationDefinitionPoorly cohesive cells gastric carcinomaReviewTherapeutic management

Identifiers

PMID36160745
PMCPMC9412924

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.