ArticleWorld journal of gastrointestinal oncology2022
Adjuvant chemoradiotherapy
Article in World journal of gastrointestinal oncology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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8 authors.
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Abstract
backgroundFor Siewert type II/III adenocarcinoma of gastroesophageal junction (AGE), the efficacy of adjuvant chemoradiotherapy (CRT) after D2/R0 resection remains uncertain.
aimTo determine whether CRT was superior to chemotherapy (CT) alone after D2/R0 resection for locally advanced Siewert type II/III AGE.
methodsWe identified 316 locally advanced Siewert type II/III AGE patients who were treated with D2/R0 resection at National Cancer Center from 2011 to 2018. 57 patients received adjuvant CRT and 259 patients received adjuvant CT. We followed patients for overall survival (OS), relapse-free survival, and recurrence pattern.
resultsFive-year OS rates of the CRT group and the CT group for all patients were 66.7% and 41.9% (
conclusionFor locally advanced Siewert type III AGE, adjuvant CRT may prolong OS and reduce the regional recurrence rate.
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