Evidence map›Paper›PMID 36160656›Full record

ArticleCase reports in neurology

Myasthenia Gravis Complicated by Eosinophilic Granulomatosis with Polyangiitis: A Case Report.

Takahumi Uchi, Shingo Konno, Hideo Kihara, Mari Matsushima, Hideki Sugimoto, Toshiaki Oharaseki, Kei Takahashi, Toshiki Fujioka

Abstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Case reports in neurology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Takahumi UchiDepartment of Neurology, Toho University Ohashi Medical Center, Tokyo, Japan.
Shingo KonnoDepartment of Neurology, Toho University Ohashi Medical Center, Tokyo, Japan.
Hideo KiharaDepartment of Neurology, Toho University Ohashi Medical Center, Tokyo, Japan.
Mari MatsushimaDepartment of Neurology, Toho University Ohashi Medical Center, Tokyo, Japan.
Hideki SugimotoDepartment of Neurology, Toho University Ohashi Medical Center, Tokyo, Japan.
Toshiaki OharasekiDepartment of Pathology, Toho University Ohashi Medical Center, Tokyo, Japan.
Kei TakahashiDepartment of Pathology, Toho University Ohashi Medical Center, Tokyo, Japan.
Toshiki FujiokaDepartment of Neurology, Toho University Ohashi Medical Center, Tokyo, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A 55-year-old woman with a history of allergic sinusitis was being administered cyclosporine for ptosis and diplopia due to myasthenia gravis since age 46 years. She developed painful dysesthesia that began in her feet and later spread to her palms, leading to difficulty in walking. Eosinophils were markedly increased in the peripheral blood. Nerve conduction studies revealed mononeuritis multiplex. Nerve biopsy showed the infiltration of eosinophils in the superior neurovasculature. Based on these findings, eosinophilic granulomatous polyangiitis was diagnosed. Methylprednisolone pulse therapy was followed by oral prednisolone. Two weeks after treatment, the patient could do normal daily activities without assistance. In patients with myasthenia gravis having a history of allergic diseases, considering EGPA as a complication and monitoring prior changes in blood data are necessary for early detection before apparent tissue damage.

Indexed as

CyclosporineEosinophilic granulomatosis with polyangiitisMethylprednisolone plus therapyMononeuropathy multiplexMyasthenia gravis

Identifiers

PMID36160656
PMCPMC9386410

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.