Evidence map›Paper›PMID 36160496›Full record

ArticleCase reports in ophthalmology

Multimodal Imaging of Unilateral Acute Maculopathy Associated with Hand, Foot, and Mouth Disease: A Case Series.

Mickael Anjou, Franck Fajnkuchen, Nicolas Nabholz, Sylvia Nghiem-Buffet, Sarah Mrejen, Audrey Giocanti-Aurégan

Abstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Case reports in ophthalmology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Multi modal imaging of pediatric unilateral macular discoid lesions.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2025
    Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Mickael AnjouOphthalmology Department, APHP, Hôpital Avicenne, Paris 13 University, Bobigny, France.
Franck FajnkuchenOphthalmology Department, APHP, Hôpital Avicenne, Paris 13 University, Bobigny, France.
Nicolas NabholzCentre Ophtalmologique des Arceaux, Montpellier, France.
Sylvia Nghiem-BuffetOphthalmology Department, APHP, Hôpital Avicenne, Paris 13 University, Bobigny, France.
Sarah MrejenCentre Ophtalmologique d'Imagerie et de Laser, Paris, France.
Audrey Giocanti-AuréganOphthalmology Department, APHP, Hôpital Avicenne, Paris 13 University, Bobigny, France.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We described clinical and multimodal imaging findings in 4 patients with unilateral acute idiopathic maculopathy (UAIM) associated with hand, foot, and mouth disease. Four eyes of 4 patients (3 women and 1 man) with a mean age of 35 years (range: 24-40 years) were included. A bacillary detachment was observed in 3 out of the 4 eyes and was strongly suspected in the remaining eye. This particular detachment was resolved within 5-10 days in our series. A choriocapillaris involvement was supported by the multimodal imaging findings. On indocyanine green angiography, a hypofluorescence was observed throughout the sequence, and OCT angiography showed a defect of the choriocapillaris perfusion. In this case series, a complete multimodal retinal assessment allowed identifying the choriocapillaris as the primary tissue involved in UAIM associated with coxsackie virus infection. In 3 out of our 4 cases, a bacillary detachment with a transient evolution was identified.

Indexed as

Acute maculopathyCoxsackie virusFluorescein angiographyHand, foot, and mouth diseaseMultimodal imaging/methodsOptical coherence tomography

Identifiers

PMID36160496
PMCPMC9459532

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.